Expasy logo

ENZYME

ENZYME entry: EC 1.1.1.351

PURL: https://purl.expasy.org/enzyme/EC/1.1.1.351
Accepted Name
phosphogluconate dehydrogenase [NAD(P)(+)-dependent, decarboxylating]
Reaction catalysed
  • 6-phospho-D-gluconate + NAD(+) = D-ribulose 5-phosphate + CO2 + NADH
  • 6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO2 + NADPH
Comment(s)
  • The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce reducing power and pentose for biosynthetic reactions.
  • Unlike EC 1.1.1.44, it is not specific for NADP(+) and can accept both cofactors with similar efficiency. cf. EC 1.1.1.343.
Cross-references
BRENDA1.1.1.351
EC2PDB1.1.1.351
ExplorEnz1.1.1.351
KEGG Ligand Database for Enzyme Nomenclature1.1.1.351
IUBMB Enzyme Nomenclature1.1.1.351
MEDLINEFind literature relating to 1.1.1.351
MetaCyc1.1.1.351
Rhea expert-curated reactions1.1.1.351

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-