A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 188.8.131.52
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|Precorrin-3A + NADH + O(2) <=> precorrin-3B + NAD(+) + H(2)O|
- An oxygen atom from dioxygen is incorporated into the macrocycle at
- In the aerobic cobalamin biosynthesis pathway, four enzymes are
involved in the conversion of precorrin-3A to precorrin-6A.
- This enzyme carries out the first of the four steps, yielding
precorrin-3B as the product.
- This is followed by three methylation reactions, which introduce a
methyl group at C-17 (CobJ; EC 184.108.40.206), C-11 (CobM; 220.127.116.11) and
C-1 (CobF; EC 18.104.22.168) of the macrocycle, giving rise to precorrin-
4, precorrin-5 and precorrin-6A, respectively.
|PRIAM enzyme-specific profiles||22.214.171.124|
|KEGG Ligand Database for Enzyme Nomenclature||126.96.36.199|
|IUBMB Enzyme Nomenclature||188.8.131.52|
|MEDLINE||Find literature relating to 184.108.40.206|
entries corresponding to 1.14.13.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-