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ENZYME

ENZYME entry: EC 1.2.1.71

PURL: https://purl.expasy.org/enzyme/EC/1.2.1.71
Accepted Name
succinylglutamate-semialdehyde dehydrogenase
Alternative Name(s)
N-succinylglutamate 5-semialdehyde dehydrogenase
SGSD
succinylglutamic semialdehyde dehydrogenase
Reaction catalysed
N-succinyl-L-glutamate 5-semialdehyde + NAD(+) + H2O = N-succinyl-L-glutamate + NADH + 2 H(+)
Comment(s)
  • This is the fourth enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine.
  • This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA.
  • The five enzymes involved in this pathway are EC 2.3.1.109, EC 3.5.3.23, EC 2.6.1.11, EC 1.2.1.71 and EC 3.5.1.96.
Cross-references
BRENDA1.2.1.71
EC2PDB1.2.1.71
ExplorEnz1.2.1.71
KEGG Ligand Database for Enzyme Nomenclature1.2.1.71
IUBMB Enzyme Nomenclature1.2.1.71
MEDLINEFind literature relating to 1.2.1.71
MetaCyc1.2.1.71
Rhea expert-curated reactions1.2.1.71
UniProtKB/Swiss-Prot
Q9AAL5, ASTD1_CAUVCQ3IFT7, ASTD1_PSET1Q12QD2, ASTD1_SHEDO
Q9A7W2, ASTD2_CAUVCQ3IC91, ASTD2_PSET1Q12JA9, ASTD2_SHEDO
Q6FCQ0, ASTD_ACIADA0KN18, ASTD_AERHHA4SK35, ASTD_AERS4
Q5E2G9, ASTD_ALIF1B5FBM2, ASTD_ALIFMB6EML5, ASTD_ALISL
B1YW19, ASTD_BURA4A0K608, ASTD_BURCHB4ECZ8, ASTD_BURCJ
Q0BGV0, ASTD_BURCMQ39I25, ASTD_BURL3A9AD19, ASTD_BURM1
Q62LN5, ASTD_BURMAA1V675, ASTD_BURMSB1JYT5, ASTD_BURO0
Q1BXP1, ASTD_BURO1A3NXG2, ASTD_BURP0Q3JQC6, ASTD_BURP1
A3NBM7, ASTD_BURP6Q63SD7, ASTD_BURPSQ2SXN9, ASTD_BURTA
A4JCW0, ASTD_BURVGB0T8I8, ASTD_CAUSKQ1QTQ7, ASTD_CHRSD
Q7NXX7, ASTD_CHRVOA8AHD8, ASTD_CITK8Q488Y0, ASTD_COLP3
A7MNV8, ASTD_CROS8A7ZML4, ASTD_ECO24B7USC7, ASTD_ECO27
B7MAV7, ASTD_ECO45B7L6M0, ASTD_ECO55Q7ADE6, ASTD_ECO57
B5YQ33, ASTD_ECO5EB7NT31, ASTD_ECO7IB7MVM5, ASTD_ECO81
B7M1F8, ASTD_ECO8AC4ZZA2, ASTD_ECOBWB1XGK7, ASTD_ECODH
A8A0T8, ASTD_ECOHSQ0TH84, ASTD_ECOL5Q8FH01, ASTD_ECOL6
B1IPI4, ASTD_ECOLCP76217, ASTD_ECOLIB7N582, ASTD_ECOLU
B6IBG6, ASTD_ECOSEB1LDY5, ASTD_ECOSMQ1RB47, ASTD_ECOUT
A4XWE7, ASTD_ECTM1A4W9J7, ASTD_ENT38B2VJX8, ASTD_ERWT9
B7LQ46, ASTD_ESCF3Q2SKP1, ASTD_HAHCHQ5QVX3, ASTD_IDILO
A6T7T5, ASTD_KLEP7Q5X4K4, ASTD_LEGPAA5ICK3, ASTD_LEGPC
Q5ZUT5, ASTD_LEGPHQ5WVZ4, ASTD_LEGPLA1U5W8, ASTD_MARN8
Q2G9T9, ASTD_NOVADQ141D3, ASTD_PARXLQ7N2G9, ASTD_PHOLL
Q6LVE5, ASTD_PHOPRQ48G19, ASTD_PSE14Q15Y60, ASTD_PSEA6
O50174, ASTD_PSEAEQ1I6Z5, ASTD_PSEE4Q4K837, ASTD_PSEF5
C3JXY7, ASTD_PSEFSA5W0D5, ASTD_PSEP1Q3K885, ASTD_PSEPF
B0KR47, ASTD_PSEPGQ88EI4, ASTD_PSEPKB1JCH3, ASTD_PSEPW
Q885J7, ASTD_PSESMQ4ZQH8, ASTD_PSEU2B5F7J0, ASTD_SALA4
A9MFG0, ASTD_SALARB5FJD6, ASTD_SALDCB5QWI8, ASTD_SALEP
B5RAZ9, ASTD_SALG2B4TGE2, ASTD_SALHSB4T3Z6, ASTD_SALNS
Q5PHC0, ASTD_SALPAA9N276, ASTD_SALPBC0Q6X8, ASTD_SALPC
B5BA70, ASTD_SALPKB4TUC3, ASTD_SALSVQ8Z6G1, ASTD_SALTI
Q8ZPV0, ASTD_SALTYA8GFQ3, ASTD_SERP5B8EBC2, ASTD_SHEB2
A3D039, ASTD_SHEB5A6WST7, ASTD_SHEB8A9L3U4, ASTD_SHEB9
Q07XY1, ASTD_SHEFNB0TU38, ASTD_SHEHHQ8EJ54, ASTD_SHEON
A8H8E0, ASTD_SHEPAA4Y344, ASTD_SHEPCB8CIT6, ASTD_SHEPW
A0KST2, ASTD_SHESAA8FRE9, ASTD_SHESHA1RNU4, ASTD_SHESW
B1KDF2, ASTD_SHEWMB2U3C8, ASTD_SHIB3Q321N8, ASTD_SHIBS
Q32G88, ASTD_SHIDSQ0T4V3, ASTD_SHIF8Q7UCI7, ASTD_SHIFL
A9EN94, ASTD_SORC5Q1GV29, ASTD_SPHALB7VLI4, ASTD_VIBA3
A7MX96, ASTD_VIBC1A5F529, ASTD_VIBC3Q9KNW4, ASTD_VIBCH
C3LRS7, ASTD_VIBCMQ87L22, ASTD_VIBPAQ8DCS9, ASTD_VIBVU
Q7MH21, ASTD_VIBVYQ1C8A9, ASTD_YERPAB2K296, ASTD_YERPB
Q9ZC68, ASTD_YERPEA9QZ61, ASTD_YERPGA4TJU5, ASTD_YERPP
Q66B19, ASTD_YERPSB1JMD1, ASTD_YERPY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-