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ENZYME

ENZYME entry: EC 2.3.1.109

PURL: https://purl.expasy.org/enzyme/EC/2.3.1.109
Accepted Name
arginine N-succinyltransferase
Alternative Name(s)
AOST
arginine and ornithine N(2)-succinyltransferase
arginine succinyltransferase
AST
Reaction catalysed
succinyl-CoA + L-arginine = N(2)-succinyl-L-arginine + CoA + H(+)
Comment(s)
  • Also acts on L-ornithine.
  • This is the first enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine.
  • This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA.
  • The five enzymes involved in this pathway are EC 2.3.1.109, EC 3.5.3.23, EC 2.6.1.81, EC 1.2.1.71 and EC 3.5.1.96.
Cross-references
BRENDA2.3.1.109
EC2PDB2.3.1.109
ExplorEnz2.3.1.109
KEGG Ligand Database for Enzyme Nomenclature2.3.1.109
IUBMB Enzyme Nomenclature2.3.1.109
MEDLINEFind literature relating to 2.3.1.109
MetaCyc2.3.1.109
Rhea expert-curated reactions2.3.1.109
UniProtKB/Swiss-Prot
A8AHD9, ASTA_CITK8A7ZML5, ASTA_ECO24B7USC8, ASTA_ECO27
B7MAV8, ASTA_ECO45B7L6M1, ASTA_ECO55P0AE38, ASTA_ECO57
B5YQ34, ASTA_ECO5EB7NT30, ASTA_ECO7IB7MVM6, ASTA_ECO81
B7M1F9, ASTA_ECO8AC4ZZA3, ASTA_ECOBWB1XGK8, ASTA_ECODH
A8A0T9, ASTA_ECOHSA1ABS8, ASTA_ECOK1Q0TH83, ASTA_ECOL5
Q8FH00, ASTA_ECOL6B1IPI3, ASTA_ECOLCP0AE37, ASTA_ECOLI
B7N583, ASTA_ECOLUB6IBG7, ASTA_ECOSEB1LDY4, ASTA_ECOSM
Q1RB46, ASTA_ECOUTA4W9J6, ASTA_ENT38B7LQ45, ASTA_ESCF3
Q7N2G8, ASTA_PHOLLP80357, ASTA_PSEAEB5F845, ASTA_SALA4
A9MFG1, ASTA_SALARB5FJD7, ASTA_SALDCB5QWI9, ASTA_SALEP
B4TGE1, ASTA_SALHSB4T3Z5, ASTA_SALNSQ5PHB9, ASTA_SALPA
A9N277, ASTA_SALPBB5BA71, ASTA_SALPKB4TUC2, ASTA_SALSV
Q8Z6G0, ASTA_SALTIQ8ZPV1, ASTA_SALTYB2U3C9, ASTA_SHIB3
Q321N9, ASTA_SHIBSQ32G89, ASTA_SHIDSQ0T4V4, ASTA_SHIF8
Q83L52, ASTA_SHIFLQ3Z294, ASTA_SHISSA1JS43, ASTA_YERE8
Q1C8B0, ASTA_YERPAB2K295, ASTA_YERPBQ9ZC67, ASTA_YERPE
A9QZ62, ASTA_YERPGA4TJU6, ASTA_YERPPQ66B20, ASTA_YERPS
B1JMD2, ASTA_YERPYP80358, ASTG_PSEAE

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
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