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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.5.3.23

Accepted Name
N-succinylarginine dihydrolase.
Alternative Name(s)
Arginine succinylhydrolase.
N(2)-succinylarginine dihydrolase.
SADH.
Reaction catalysed
N(2)-succinyl-L-arginine + 2 H(2)O <=> N(2)-succinyl-L-ornithine + 2 NH(3) + CO(2)
Comment(s)
  • Arginine, N(2)-acetylarginine and N(2)-glutamylarginine do not act as substrates.
  • The second enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine.
  • This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA.
  • The five enzymes involved in this pathway are EC 2.3.1.109, EC 3.5.3.23, EC 2.6.1.11, EC 1.2.1.71 and EC 3.5.1.96.
Cross-references
BRENDA3.5.3.23
EC2PDB3.5.3.23
ExplorEnz3.5.3.23
PRIAM enzyme-specific profiles3.5.3.23
KEGG Ligand Database for Enzyme Nomenclature3.5.3.23
IUBMB Enzyme Nomenclature3.5.3.23
IntEnz3.5.3.23
MEDLINEFind literature relating to 3.5.3.23
MetaCyc3.5.3.23
UniProtKB/Swiss-Prot
Q9AAL4, ASTB1_CAUVC;  Q9A7W1, ASTB2_CAUVC;  Q6FCP9, ASTB_ACIAD;  
B7GVV0, ASTB_ACIB3;  B7IA89, ASTB_ACIB5;  B2HZS3, ASTB_ACIBC;  
B0VQ88, ASTB_ACIBS;  A3M9D2, ASTB_ACIBT;  B0V7X3, ASTB_ACIBY;  
A0KMV4, ASTB_AERHH;  Q5DZ79, ASTB_ALIF1;  B5EV09, ASTB_ALIFM;  
B6EQ59, ASTB_ALISL;  B1YW20, ASTB_BURA4;  Q1BXP0, ASTB_BURCA;  
B1JYT6, ASTB_BURCC;  A0K609, ASTB_BURCH;  B4ECZ9, ASTB_BURCJ;  
Q0BGU9, ASTB_BURCM;  Q39I24, ASTB_BURL3;  A9AD18, ASTB_BURM1;  
A3MLY7, ASTB_BURM7;  A2SA47, ASTB_BURM9;  Q62LN4, ASTB_BURMA;  
A1V674, ASTB_BURMS;  A3NXG1, ASTB_BURP0;  Q3JQC7, ASTB_BURP1;  
A3NBM6, ASTB_BURP6;  Q63SD8, ASTB_BURPS;  Q2SXN8, ASTB_BURTA;  
A4JCW1, ASTB_BURVG;  Q1QTQ8, ASTB_CHRSD;  Q7NXX6, ASTB_CHRVO;  
A8AHD7, ASTB_CITK8;  A7MNV7, ASTB_CROS8;  A7ZML3, ASTB_ECO24;  
B7USC6, ASTB_ECO27;  B7MAV6, ASTB_ECO45;  B7L6L9, ASTB_ECO55;  
Q7ADE7, ASTB_ECO57;  B5YQ32, ASTB_ECO5E;  B7NT32, ASTB_ECO7I;  
B7MVM4, ASTB_ECO81;  B7M1F7, ASTB_ECO8A;  C4ZZA1, ASTB_ECOBW;  
B1XGK6, ASTB_ECODH;  A8A0T7, ASTB_ECOHS;  A1ABS6, ASTB_ECOK1;  
Q0TH85, ASTB_ECOL5;  Q8FH02, ASTB_ECOL6;  B1IPI5, ASTB_ECOLC;  
P76216, ASTB_ECOLI;  B7N581, ASTB_ECOLU;  B6IBG5, ASTB_ECOSE;  
B1LDY6, ASTB_ECOSM;  Q1RB48, ASTB_ECOUT;  A4W9J8, ASTB_ENT38;  
B2VEK6, ASTB_ERWT9;  B7LQ47, ASTB_ESCF3;  Q2SKP0, ASTB_HAHCH;  
Q5QWI1, ASTB_IDILO;  Q5X4K3, ASTB_LEGPA;  A5ICK4, ASTB_LEGPC;  
Q5ZUT4, ASTB_LEGPH;  Q5WVZ3, ASTB_LEGPL;  A1U5W7, ASTB_MARHV;  
Q1DDF6, ASTB_MYXXD;  Q2Y8M6, ASTB_NITMU;  Q2G9Z6, ASTB_NOVAD;  
B2JCG4, ASTB_PARP8;  B2T314, ASTB_PARPJ;  Q141D2, ASTB_PARXL;  
Q7N2H0, ASTB_PHOLL;  Q6LJR6, ASTB_PHOPR;  Q48G20, ASTB_PSE14;  
Q15TB5, ASTB_PSEA6;  A6VA75, ASTB_PSEA7;  B7UY35, ASTB_PSEA8;  
Q02I59, ASTB_PSEAB;  O50175, ASTB_PSEAE;  Q1I6Z6, ASTB_PSEE4;  
Q4K838, ASTB_PSEF5;  C3JXY6, ASTB_PSEFS;  Q3ID31, ASTB_PSEHT;  
A4XWE6, ASTB_PSEMY;  A5W0D6, ASTB_PSEP1;  Q3K886, ASTB_PSEPF;  
B0KR46, ASTB_PSEPG;  Q88EI5, ASTB_PSEPK;  B1JCH2, ASTB_PSEPW;  
Q885J6, ASTB_PSESM;  Q4ZQH9, ASTB_PSEU2;  B5F7I9, ASTB_SALA4;  
A9MFF9, ASTB_SALAR;  B5FJD5, ASTB_SALDC;  B5QWI7, ASTB_SALEP;  
B5RAZ8, ASTB_SALG2;  B4TGE3, ASTB_SALHS;  B4T3Z7, ASTB_SALNS;  
Q5PHC1, ASTB_SALPA;  A9N275, ASTB_SALPB;  B5BA69, ASTB_SALPK;  
B4TUC4, ASTB_SALSV;  Q8Z6G2, ASTB_SALTI;  Q8ZPU9, ASTB_SALTY;  
A8GFQ2, ASTB_SERP5;  A1S572, ASTB_SHEAM;  B8E786, ASTB_SHEB2;  
A3D5H7, ASTB_SHEB5;  A6WP88, ASTB_SHEB8;  A9L516, ASTB_SHEB9;  
Q12LR7, ASTB_SHEDO;  Q080J1, ASTB_SHEFN;  B0TP13, ASTB_SHEHH;  
A3QF43, ASTB_SHELP;  Q8EDN7, ASTB_SHEON;  A8H2S2, ASTB_SHEPA;  
A4Y7N9, ASTB_SHEPC;  B8CN09, ASTB_SHEPW;  A0KVZ2, ASTB_SHESA;  
A8FX76, ASTB_SHESH;  A1RIU9, ASTB_SHESW;  B1KNK9, ASTB_SHEWM;  
Q321N7, ASTB_SHIBS;  Q32G87, ASTB_SHIDS;  Q3Z293, ASTB_SHISS;  
Q1GRR9, ASTB_SPHAL;  A5V3M9, ASTB_SPHWW;  A1JS35, ASTB_YERE8;  
A7FIL3, ASTB_YERP3;  Q1C8A8, ASTB_YERPA;  B2K297, ASTB_YERPB;  
Q8D0D8, ASTB_YERPE;  A9QZ60, ASTB_YERPG;  A4TJU4, ASTB_YERPP;  
Q66B18, ASTB_YERPS;  B1JMD0, ASTB_YERPY;  Q5NNB4, ASTB_ZYMMO;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-