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ENZYME

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ENZYME entry: EC 3.5.3.23

Accepted Name
N-succinylarginine dihydrolase
Alternative Name(s)
arginine succinylhydrolase
N(2)-succinylarginine dihydrolase
SADH
Reaction catalysed
2 H(+) + 2 H2O + N(2)-succinyl-L-arginine = CO2 + N(2)-succinyl-L-ornithine + 2 NH4(+)
Comment(s)
  • Arginine, N(2)-acetylarginine and N(2)-glutamylarginine do not act as substrates.
  • The second enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine.
  • This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA.
  • The five enzymes involved in this pathway are EC 2.3.1.109, EC 3.5.3.23, EC 2.6.1.11, EC 1.2.1.71 and EC 3.5.1.96.
Cross-references
BRENDA3.5.3.23
EC2PDB3.5.3.23
ExplorEnz3.5.3.23
PRIAM enzyme-specific profiles3.5.3.23
KEGG Ligand Database for Enzyme Nomenclature3.5.3.23
IUBMB Enzyme Nomenclature3.5.3.23
IntEnz3.5.3.23
MEDLINEFind literature relating to 3.5.3.23
MetaCyc3.5.3.23
Rhea expert-curated reactions3.5.3.23
UniProtKB/Swiss-Prot
Q9AAL4, ASTB1_CAUVCQ9A7W1, ASTB2_CAUVCQ6FCP9, ASTB_ACIAD
B7GVV0, ASTB_ACIB3B7IA89, ASTB_ACIB5B2HZS3, ASTB_ACIBC
B0VQ88, ASTB_ACIBSA3M9D2, ASTB_ACIBTB0V7X3, ASTB_ACIBY
A0KMV4, ASTB_AERHHQ5DZ79, ASTB_ALIF1B5EV09, ASTB_ALIFM
B6EQ59, ASTB_ALISLB1YW20, ASTB_BURA4A0K609, ASTB_BURCH
B4ECZ9, ASTB_BURCJQ0BGU9, ASTB_BURCMQ39I24, ASTB_BURL3
A9AD18, ASTB_BURM1A3MLY7, ASTB_BURM7A2SA47, ASTB_BURM9
Q62LN4, ASTB_BURMAA1V674, ASTB_BURMSB1JYT6, ASTB_BURO0
Q1BXP0, ASTB_BURO1A3NXG1, ASTB_BURP0Q3JQC7, ASTB_BURP1
A3NBM6, ASTB_BURP6Q63SD8, ASTB_BURPSQ2SXN8, ASTB_BURTA
A4JCW1, ASTB_BURVGQ1QTQ8, ASTB_CHRSDQ7NXX6, ASTB_CHRVO
A8AHD7, ASTB_CITK8A7MNV7, ASTB_CROS8A7ZML3, ASTB_ECO24
B7USC6, ASTB_ECO27B7MAV6, ASTB_ECO45B7L6L9, ASTB_ECO55
Q7ADE7, ASTB_ECO57B5YQ32, ASTB_ECO5EB7NT32, ASTB_ECO7I
B7MVM4, ASTB_ECO81B7M1F7, ASTB_ECO8AC4ZZA1, ASTB_ECOBW
B1XGK6, ASTB_ECODHA8A0T7, ASTB_ECOHSA1ABS6, ASTB_ECOK1
Q0TH85, ASTB_ECOL5Q8FH02, ASTB_ECOL6B1IPI5, ASTB_ECOLC
P76216, ASTB_ECOLIB7N581, ASTB_ECOLUB6IBG5, ASTB_ECOSE
B1LDY6, ASTB_ECOSMQ1RB48, ASTB_ECOUTA4W9J8, ASTB_ENT38
B2VEK6, ASTB_ERWT9B7LQ47, ASTB_ESCF3Q2SKP0, ASTB_HAHCH
Q5QWI1, ASTB_IDILOQ5X4K3, ASTB_LEGPAA5ICK4, ASTB_LEGPC
Q5ZUT4, ASTB_LEGPHQ5WVZ3, ASTB_LEGPLA1U5W7, ASTB_MARN8
Q1DDF6, ASTB_MYXXDQ2Y8M6, ASTB_NITMUQ2G9Z6, ASTB_NOVAD
B2JCG4, ASTB_PARP8B2T314, ASTB_PARPJQ141D2, ASTB_PARXL
Q7N2H0, ASTB_PHOLLQ6LJR6, ASTB_PHOPRQ48G20, ASTB_PSE14
Q15TB5, ASTB_PSEA6A6VA75, ASTB_PSEA7B7UY35, ASTB_PSEA8
Q02I59, ASTB_PSEABO50175, ASTB_PSEAEQ1I6Z6, ASTB_PSEE4
Q4K838, ASTB_PSEF5C3JXY6, ASTB_PSEFSA4XWE6, ASTB_PSEMY
A5W0D6, ASTB_PSEP1Q3K886, ASTB_PSEPFB0KR46, ASTB_PSEPG
Q88EI5, ASTB_PSEPKB1JCH2, ASTB_PSEPWQ885J6, ASTB_PSESM
Q3ID31, ASTB_PSET1Q4ZQH9, ASTB_PSEU2A5V3M9, ASTB_RHIWR
B5F7I9, ASTB_SALA4A9MFF9, ASTB_SALARB5FJD5, ASTB_SALDC
B5QWI7, ASTB_SALEPB5RAZ8, ASTB_SALG2B4TGE3, ASTB_SALHS
B4T3Z7, ASTB_SALNSQ5PHC1, ASTB_SALPAA9N275, ASTB_SALPB
B5BA69, ASTB_SALPKB4TUC4, ASTB_SALSVQ8Z6G2, ASTB_SALTI
Q8ZPU9, ASTB_SALTYA8GFQ2, ASTB_SERP5A1S572, ASTB_SHEAM
B8E786, ASTB_SHEB2A3D5H7, ASTB_SHEB5A6WP88, ASTB_SHEB8
A9L516, ASTB_SHEB9Q12LR7, ASTB_SHEDOQ080J1, ASTB_SHEFN
B0TP13, ASTB_SHEHHA3QF43, ASTB_SHELPQ8EDN7, ASTB_SHEON
A8H2S2, ASTB_SHEPAA4Y7N9, ASTB_SHEPCB8CN09, ASTB_SHEPW
A0KVZ2, ASTB_SHESAA8FX76, ASTB_SHESHA1RIU9, ASTB_SHESW
B1KNK9, ASTB_SHEWMQ321N7, ASTB_SHIBSQ32G87, ASTB_SHIDS
Q3Z293, ASTB_SHISSQ1GRR9, ASTB_SPHALA1JS35, ASTB_YERE8
A7FIL3, ASTB_YERP3Q1C8A8, ASTB_YERPAB2K297, ASTB_YERPB
Q8D0D8, ASTB_YERPEA9QZ60, ASTB_YERPGA4TJU4, ASTB_YERPP
Q66B18, ASTB_YERPSB1JMD0, ASTB_YERPYQ5NNB4, ASTB_ZYMMO

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-