Expasy logo

ENZYME

Due to maintenance work, this service will be unavailable on Monday between 06:00 until 06:30 CEST. Apologies for the inconvenience.

ENZYME entry: EC 1.2.1.72

Accepted Name
erythrose-4-phosphate dehydrogenase
Alternative Name(s)
E4P dehydrogenase
E4PDH
erythrose 4-phosphate dehydrogenase
Reaction catalysed
D-erythrose 4-phosphate + H2O + NAD(+) = 4-phospho-D-erythronate + 2 H(+) + NADH
Comment(s)
  • Was originally thought to be an EC 1.2.1.12, but this has since been disproved, as glyceraldehyde 3-phosphate is not a substrate.
  • Forms part of the pyridoxal-5'-phosphate cofactor biosynthesis pathway in Escherichia coli, along with EC 1.1.1.290, EC 2.6.1.52, EC 1.1.1.262, EC 2.6.99.2 and EC 1.4.3.5.
Cross-references
BRENDA1.2.1.72
EC2PDB1.2.1.72
ExplorEnz1.2.1.72
PRIAM enzyme-specific profiles1.2.1.72
KEGG Ligand Database for Enzyme Nomenclature1.2.1.72
IUBMB Enzyme Nomenclature1.2.1.72
IntEnz1.2.1.72
MEDLINEFind literature relating to 1.2.1.72
MetaCyc1.2.1.72
Rhea expert-curated reactions1.2.1.72
UniProtKB/Swiss-Prot
A0KGD2, E4PD_AERHHA4SRF2, E4PD_AERS4Q5E7R0, E4PD_ALIF1
B5F9T4, E4PD_ALIFMB6EMW1, E4PD_ALISLB4RWC5, E4PD_ALTMD
A8APE1, E4PD_CITK8Q47XD5, E4PD_COLP3A7MJQ2, E4PD_CROS8
A7ZR35, E4PD_ECO24B7UHW9, E4PD_ECO27B7MMA9, E4PD_ECO45
B7LFI3, E4PD_ECO55P0A9B8, E4PD_ECO57B5YQB9, E4PD_ECO5E
B7NHY6, E4PD_ECO7IB7MZM0, E4PD_ECO81B7LYU4, E4PD_ECO8A
C5A0J7, E4PD_ECOBWB1XEL0, E4PD_ECODHA8A467, E4PD_ECOHS
A1AFB1, E4PD_ECOK1Q0TDS9, E4PD_ECOL5P0A9B7, E4PD_ECOL6
B1IT76, E4PD_ECOLCP0A9B6, E4PD_ECOLIB7N7H3, E4PD_ECOLU
B6I761, E4PD_ECOSEB1LDD2, E4PD_ECOSMQ1R7A6, E4PD_ECOUT
C5BAU7, E4PD_EDWI9A4WE72, E4PD_ENT38B2VF24, E4PD_ERWT9
B7LPD5, E4PD_ESCF3Q5QVL6, E4PD_IDILOB5XUB7, E4PD_KLEP3
A6TDT2, E4PD_KLEP7Q6D086, E4PD_PECASC6DFH8, E4PD_PECCP
Q7N7Z6, E4PD_PHOLLQ6LMN0, E4PD_PHOPRB4EUH7, E4PD_PROMH
Q15QK3, E4PD_PSEA6Q3ILL8, E4PD_PSET1A1SVN9, E4PD_PSYIN
B5F5J5, E4PD_SALA4A9MRF0, E4PD_SALARQ57K44, E4PD_SALCH
B5FUI3, E4PD_SALDCB5QXJ7, E4PD_SALEPB5RE31, E4PD_SALG2
B4THF4, E4PD_SALHSB4T5H2, E4PD_SALNSQ5PJI5, E4PD_SALPA
A9N3Q6, E4PD_SALPBC0PY46, E4PD_SALPCB5BFN5, E4PD_SALPK
B4TV39, E4PD_SALSVQ8XGA4, E4PD_SALTIQ7CPU5, E4PD_SALTY
A1S9A4, E4PD_SHEAMB8E5U5, E4PD_SHEB2Q12QA4, E4PD_SHEDO
Q087Q7, E4PD_SHEFNB0TUC0, E4PD_SHEHHA3QAX7, E4PD_SHELP
Q8EIB2, E4PD_SHEONA8H0M9, E4PD_SHEPAA4Y3R9, E4PD_SHEPC
B8CU41, E4PD_SHEPWA0L0K7, E4PD_SHESAQ0HM63, E4PD_SHESM
Q0HRM3, E4PD_SHESRA1RN69, E4PD_SHESWB2U0U3, E4PD_SHIB3
Q31WI6, E4PD_SHIBSQ32BY7, E4PD_SHIDSQ0T0X3, E4PD_SHIF8
P0A9B9, E4PD_SHIFLQ3YXU5, E4PD_SHISSC4L9J3, E4PD_TOLAT
A7MTQ2, E4PD_VIBC1A5F9G1, E4PD_VIBC3P0C6C2, E4PD_VIBCH
Q87LL0, E4PD_VIBPAQ8DCA1, E4PD_VIBVUQ7MHL0, E4PD_VIBVY
A1JPR1, E4PD_YERE8Q1CB62, E4PD_YERPAQ7CGS4, E4PD_YERPE
Q1CEY2, E4PD_YERPNQ666Q0, E4PD_YERPS

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-