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ENZYME entry: EC 1.3.1.93

Accepted Name
Very-long-chain enoyl-CoA reductase.
Reaction catalysed
A very-long-chain acyl-CoA + NADP(+) <=> a very-long-chain trans-2,3-dehydroacyl-CoA + NADPH
Comment(s)
  • This is the fourth component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs.
  • Cf. EC 2.3.1.199, EC 1.1.1.330 and EC 4.2.1.134.
  • Formerly EC 2.3.1.119.
Cross-references
BRENDA1.3.1.93
EC2PDB1.3.1.93
ExplorEnz1.3.1.93
PRIAM enzyme-specific profiles1.3.1.93
KEGG Ligand Database for Enzyme Nomenclature1.3.1.93
IUBMB Enzyme Nomenclature1.3.1.93
IntEnz1.3.1.93
MEDLINEFind literature relating to 1.3.1.93
MetaCyc1.3.1.93
UniProtKB/Swiss-Prot
Q9M2U2, TECR_ARATH;  Q3ZCD7, TECR_BOVIN;  Q9N5Y2, TECR_CAEEL;  
Q55C17, TECR_DICDI;  Q9NZ01, TECR_HUMAN;  Q9CY27, TECR_MOUSE;  
Q64232, TECR_RAT;  Q99190, TECR_YEAST;  

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