A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.3.8.9
| Accepted Name |
|---|
| Very-long-chain acyl-CoA dehydrogenase.
|
| Reaction catalysed |
|---|
| A very-long-chain acyl-CoA + electron-transfer flavoprotein <=> a very-long-chain trans-2,3-dehydroacyl-CoA + reduced electron-transfer flavoprotein |
| Cofactor(s) |
|---|
| FAD.
|
| Comment(s) |
|---|
- One of several enzymes that catalyze the first step in fatty acids
beta-oxidation.
- The enzyme is most active toward long-chain acyl-CoAs such as C(14),
C(16) and C(18), but is also active with very-long-chain acyl-CoAs up
to 24 carbons.
- It shows no activity for substrates of less than 12 carbons.
- It's specific activity toward palmitoyl-CoA is more than 10-fold that
of the long-chain acyl-CoA dehydrogenase.
- cf. EC 1.3.8.1, EC 1.3.8.7 and EC 1.3.8.8.
- Formerly EC 1.3.99.3.
|
| Cross-references |
|---|
| BRENDA | 1.3.8.9 |
| EC2PDB | 1.3.8.9 |
| ExplorEnz | 1.3.8.9 |
| PRIAM enzyme-specific profiles | 1.3.8.9 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.3.8.9 |
| IUBMB Enzyme Nomenclature | 1.3.8.9 |
| IntEnz | 1.3.8.9 |
| MEDLINE | Find literature relating to 1.3.8.9 |
| MetaCyc | 1.3.8.9 |
| UniProtKB/Swiss-Prot |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.3.8.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-