ENZYME

ENZYME entry: EC 1.5.3.14

Accepted Name

Polyamine oxidase (propane-1,3-diamine-forming).

Alternative Name(s)

Maize PAO.

MPAO.

Reaction catalysed

Spermidine + O(2) + H(2)O <=> propane-1,3-diamine + 4-aminobutanal + H(2)O(2)

Cofactor(s)

FAD.

Comment(s)

As the products of the reaction cannot be converted directly to other polyamines, this class of polyamine oxidases is considered to be involved in the terminal catabolism of polyamines.
Catalyzes less efficiently the oxidation of N(1)-acetylspermine and spermine.
Differs in specificity from EC 1.5.3.13, EC 1.5.3.15, EC 1.5.3.16 and EC 1.5.3.17.
Formerly EC 1.5.3.11, EC 1.5.3.n6, EC 1.5.3.n7, EC 1.5.3.n8 and EC 1.5.3.n9.