ENZYME entry: EC 1.5.3.16
Accepted Name |
Spermine oxidase.
|
Alternative Name(s) |
SMO. |
Reaction catalysed |
Spermine + O(2) + H(2)O <=> spermidine + 3-aminopropanal + H(2)O(2) |
Cofactor(s) |
FAD.
|
Comment(s) |
- The enzyme from Arabidopsis thaliana (AtPAO1) oxidizes norspermine to
norspermidine with high efficiency.
- The mammalian enzyme, encoded by the SMOX gene, is a cytosolic enzyme
that catalyzes the oxidation of spermine at the exo (three-carbon)
side of the tertiary amine.
- No activity with spermidine.
- Weak activity with N(1)-acetylspermine.
- Differs in specificity from EC 1.5.3.13, EC 1.5.3.14, EC 1.5.3.15 and
EC 1.5.3.17.
- Formerly EC 1.5.3.11, EC 1.5.3.n1, EC 1.5.3.n2, EC 1.5.3.n3 and
EC 1.5.3.n5.
|
Cross-references |
BRENDA | 1.5.3.16 |
EC2PDB | 1.5.3.16 |
ExplorEnz | 1.5.3.16 |
PRIAM enzyme-specific profiles | 1.5.3.16 |
KEGG Ligand Database for Enzyme Nomenclature | 1.5.3.16 |
IUBMB Enzyme Nomenclature | 1.5.3.16 |
IntEnz | 1.5.3.16 |
MEDLINE | Find literature relating to 1.5.3.16 |
MetaCyc | 1.5.3.16 |
UniProtKB/Swiss-Prot |
|
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