Expasy logo

ENZYME

ENZYME entry: EC 1.8.1.5

PURL: https://purl.expasy.org/enzyme/EC/1.8.1.5
Accepted Name
2-oxopropyl-CoM reductase (carboxylating)
Alternative Name(s)
2-KPCC
NADPH:2-(2-ketopropylthio)ethanesulfonate oxidoreductase/carboxylase
NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase
Reaction catalysed
coenzyme M + acetoacetate + NADP(+) = 2-oxopropyl-coenzyme M + CO2 + NADPH
Comment(s)
  • Also acts on thioethers longer in chain length on the oxo side, e.g. 2-oxobutyl-CoM, but this portion must be attached to CoM (2-sulfanylethane-1-sulfonate); no CoM analogs will substitute.
  • Forms component II of a four-component enzyme system (comprising EC 4.4.1.23 (component I), EC 1.8.1.5 (component II), EC 1.1.1.268 (component III) and EC 1.1.1.269 (component IV)) that is involved in epoxyalkane carboxylation in Xanthobacter sp. strain Py2.
Cross-references
BRENDA1.8.1.5
EC2PDB1.8.1.5
ExplorEnz1.8.1.5
KEGG Ligand Database for Enzyme Nomenclature1.8.1.5
IUBMB Enzyme Nomenclature1.8.1.5
MEDLINEFind literature relating to 1.8.1.5
MetaCyc1.8.1.5
Rhea expert-curated reactions1.8.1.5
UniProtKB/Swiss-Prot
Q56839, XECC_XANP2

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-