A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.8.1.5
| Accepted Name |
|---|
| 2-oxopropyl-CoM reductase (carboxylating).
|
| Alternative Name(s) |
|---|
| 2-KPCC. |
| NADPH:2-(2-ketopropylthio)ethanesulfonate oxidoreductase/carboxylase. |
| NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase. |
| Reaction catalysed |
|---|
| 2-mercaptoethanesulfonate + acetoacetate + NADP(+) <=> 2-(2-oxopropylthio)ethanesulfonate + CO(2) + NADPH |
| Comment(s) |
|---|
- Also acts on thioethers longer in chain length on the oxo side, e.g.
2-oxobutyl-CoM, but this portion must be attached to CoM
(2-mercaptoethanesulfonate); no CoM analogs will substitute.
- Forms component II of a four-component enzyme system (comprising
EC 4.4.1.23 (component I), EC 1.8.1.5 (component II), EC 1.1.1.268
(component III) and EC 1.1.1.269 (component IV)) that is involved in
epoxyalkane carboxylation in Xanthobacter sp. strain Py2.
|
| Cross-references |
|---|
| BRENDA | 1.8.1.5 |
| EC2PDB | 1.8.1.5 |
| ExplorEnz | 1.8.1.5 |
| PRIAM enzyme-specific profiles | 1.8.1.5 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.8.1.5 |
| IUBMB Enzyme Nomenclature | 1.8.1.5 |
| IntEnz | 1.8.1.5 |
| MEDLINE | Find literature relating to 1.8.1.5 |
| MetaCyc | 1.8.1.5 |
| UniProtKB/Swiss-Prot |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.8.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-