Expasy logo

ENZYME

ENZYME entry: EC 2.3.1.61

PURL: https://purl.expasy.org/enzyme/EC/2.3.1.61
Accepted Name
dihydrolipoyllysine-residue succinyltransferase
Alternative Name(s)
dihydrolipoamide S-succinyltransferase
dihydrolipoamide succinyltransferase
dihydrolipoic transsuccinylase
dihydrolipolyl transsuccinylase
dihydrolipoyl transsuccinylase
lipoate succinyltransferase
lipoic transsuccinylase
lipoyl transsuccinylase
succinyl-CoA:dihydrolipoamide S-succinyltransferase
succinyl-CoA:dihydrolipoate S-succinyltransferase
Reaction catalysed
N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + succinyl-CoA = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[protein] + CoA
Comment(s)
  • A multimer (24-mer) of this enzyme forms the core of the multienzyme complex, and binds tightly both EC 1.2.4.2 and EC 1.8.1.4.
  • The lipoyl group of this enzyme is reductively succinylated by EC 1.2.4.2, and the only observed direction catalyzed by EC 2.3.1.61 is that where this succinyl group is passed to coenzyme A.
Cross-references
BRENDA2.3.1.61
EC2PDB2.3.1.61
ExplorEnz2.3.1.61
KEGG Ligand Database for Enzyme Nomenclature2.3.1.61
IUBMB Enzyme Nomenclature2.3.1.61
MEDLINEFind literature relating to 2.3.1.61
MetaCyc2.3.1.61
Rhea expert-curated reactions2.3.1.61
UniProtKB/Swiss-Prot
Q7U0A6, KGD_MYCBOA1KI36, KGD_MYCBPQ9CC97, KGD_MYCLE
Q73WX4, KGD_MYCPAA0R2B1, KGD_MYCS2A3Q3N5, KGD_MYCSJ
A1UK81, KGD_MYCSKQ1B4V6, KGD_MYCSSA5U1U6, KGD_MYCTA
P9WIS4, KGD_MYCTOP9WIS5, KGD_MYCTUA0PVU7, KGD_MYCUA
A1TDK2, KGD_MYCVPQ8NRC3, ODO12_CORGLQ9FLQ4, ODO2A_ARATH
Q8H107, ODO2B_ARATHP20708, ODO2_AZOVIP16263, ODO2_BACSU
Q6FYD4, ODO2_BARQUQ8GCY1, ODO2_BARVBP11179, ODO2_BOVIN
P57389, ODO2_BUCAIQ8K9N2, ODO2_BUCAPQ89AJ6, ODO2_BUCBP
P52993, ODO2_CUPNHP83708, ODO2_DELACQ869Y7, ODO2_DICDI
P0AFG7, ODO2_ECO57P0AFG6, ODO2_ECOLIP45302, ODO2_HAEIN
P36957, ODO2_HUMANP86219, ODO2_MESAUQ9D2G2, ODO2_MOUSE
Q9N0F1, ODO2_PIGQ9I3D2, ODO2_PSEAEP31051, ODO2_PSEPU
Q01205, ODO2_RATQ1RHI5, ODO2_RICBRQ92J43, ODO2_RICCN
Q4UKI7, ODO2_RICFEQ9ZDY4, ODO2_RICPRQ68XI8, ODO2_RICTY
O94681, ODO2_SCHPOP81896, ODO2_SOLTUQ2FH26, ODO2_STAA3
Q2FYM2, ODO2_STAA8Q2YY06, ODO2_STAABQ5HG07, ODO2_STAAC
Q99U75, ODO2_STAAMQ7A5N4, ODO2_STAANQ6GGZ6, ODO2_STAAR
Q6G9E9, ODO2_STAASQ8NWR7, ODO2_STAAWQ5HPC7, ODO2_STAEQ
Q8CSL9, ODO2_STAESQ4L6C3, ODO2_STAHJQ49XM4, ODO2_STAS1
Q90512, ODO2_TAKRUP19262, ODO2_YEAST

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-