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ENZYME

ENZYME entry: EC 2.4.2.18

PURL: https://purl.expasy.org/enzyme/EC/2.4.2.18
Accepted Name
anthranilate phosphoribosyltransferase
Alternative Name(s)
phosphoribosyl-anthranilate diphosphorylase
phosphoribosyl-anthranilate pyrophosphorylase
Reaction catalysed
N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate
Comment(s)
In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 4.1.1.48, EC 4.1.3.27, EC 4.2.1.20 and EC 5.3.1.24).
Cross-references
BRENDA2.4.2.18
EC2PDB2.4.2.18
ExplorEnz2.4.2.18
KEGG Ligand Database for Enzyme Nomenclature2.4.2.18
IUBMB Enzyme Nomenclature2.4.2.18
MEDLINEFind literature relating to 2.4.2.18
MetaCyc2.4.2.18
Rhea expert-curated reactions2.4.2.18
UniProtKB/Swiss-Prot
O28668, TRPCD_ARCFUQ8YZP8, TRPD1_NOSS1Q8XVE7, TRPD1_RALN1
O68608, TRPD1_STRCOQ8YXQ9, TRPD2_NOSS1Q8XS00, TRPD2_RALN1
Q9Z4W9, TRPD2_STRCOA3DDS8, TRPD_ACET2P00500, TRPD_ACIAD
B0VUS1, TRPD_ACIBSA3M784, TRPD_ACIBTB0VBS2, TRPD_ACIBY
A0LTH9, TRPD_ACIC1B9MBS3, TRPD_ACIETB7JBC1, TRPD_ACIF2
B5ERI3, TRPD_ACIF5A1W2Z7, TRPD_ACISJA3N1G7, TRPD_ACTP2
B3GY52, TRPD_ACTP7B0BQA6, TRPD_ACTPJA6VNT3, TRPD_ACTSZ
A0KMC8, TRPD_AERHHQ9Y8T2, TRPD_AERPEA4SKT3, TRPD_AERS4
B6JG28, TRPD_AFIC5C4ZI69, TRPD_AGARVQ8UER8, TRPD_AGRFC
Q21SE7, TRPD_ALBFTQ0VMX5, TRPD_ALCBSQ0A6E7, TRPD_ALKEH
A6TM73, TRPD_ALKMQB9JX63, TRPD_ALLAMB8JAL5, TRPD_ANAD2
Q2IGV6, TRPD_ANADEA7H793, TRPD_ANADFB4UHD1, TRPD_ANASK
O66576, TRPD_AQUAEQ02166, TRPD_ARATHQ5P2G2, TRPD_AROAE
A0JX18, TRPD_ARTS2P26924, TRPD_AZOBRA8I839, TRPD_AZOC5
A1KAT3, TRPD_AZOSBC1DHY8, TRPD_AZOVDC3P3T7, TRPD_BACAA
C3LAW1, TRPD_BACACA0RB61, TRPD_BACAHQ81TM1, TRPD_BACAN
B7JES7, TRPD_BACC0Q73BR0, TRPD_BACC1B7IM73, TRPD_BACC2
C1ELE7, TRPD_BACC3B7HGZ8, TRPD_BACC4B7I0E9, TRPD_BACC7
P30525, TRPD_BACCAB9IU35, TRPD_BACCQQ81GG8, TRPD_BACCR
Q63ED0, TRPD_BACCZQ5LBZ5, TRPD_BACFNQ64SX6, TRPD_BACFR
Q6HLU7, TRPD_BACHKQ65I32, TRPD_BACLDA9VJV9, TRPD_BACMK
A8FEK1, TRPD_BACP2P18261, TRPD_BACPUP03947, TRPD_BACSU
Q8AAD5, TRPD_BACTNA7Z619, TRPD_BACVZB2IKP4, TRPD_BEII9
Q494D8, TRPD_BLOPBQ2KU98, TRPD_BORA1Q7WEK7, TRPD_BORBR
Q7W388, TRPD_BORPAA9HY12, TRPD_BORPDQ7VU66, TRPD_BORPE
P94326, TRPD_BRADUA5EK24, TRPD_BRASBA4YVD5, TRPD_BRASO
C0ZCE2, TRPD_BREBNB2S5Z0, TRPD_BRUA1Q2YRR5, TRPD_BRUA2
A6X0L1, TRPD_BRUA4Q57CZ9, TRPD_BRUABA9M5F3, TRPD_BRUC2
C0RJB0, TRPD_BRUMBQ8YHF7, TRPD_BRUMEA5VQR4, TRPD_BRUO2
B0CGT8, TRPD_BRUSIQ8G0F5, TRPD_BRUSUB8D972, TRPD_BUCA5
P57367, TRPD_BUCAIP42392, TRPD_BUCAPB8D7H6, TRPD_BUCAT
P59415, TRPD_BUCBPO68426, TRPD_BUCDNQ9RQ35, TRPD_BUCMH
Q44602, TRPD_BUCSCB1YSF6, TRPD_BURA4A0K459, TRPD_BURCH
B4E7A8, TRPD_BURCJQ0BIM7, TRPD_BURCMQ39JZ6, TRPD_BURL3
Q845X9, TRPD_BURM1A3MFQ3, TRPD_BURM7A2RYI2, TRPD_BURM9
Q62DC9, TRPD_BURMAA1UW99, TRPD_BURMSB1JUU6, TRPD_BURO0
Q1BSD3, TRPD_BURO1A3NZP5, TRPD_BURP0Q3JNB1, TRPD_BURP1
A3NDZ2, TRPD_BURP6Q63QH1, TRPD_BURPSQ2SUI1, TRPD_BURTA
A4JB68, TRPD_BURVGB9MKD0, TRPD_CALBDA8MDL8, TRPD_CALMQ
Q8R9M6, TRPD_CALS4A4XLM7, TRPD_CALS8Q3ABS0, TRPD_CARHZ
B0SYZ3, TRPD_CAUSKQ9A728, TRPD_CAUVCB8GWP8, TRPD_CAUVN
B3PLP1, TRPD_CELJUA0RX34, TRPD_CENSYA3PHK8, TRPD_CERS1
Q9ZFA8, TRPD_CERS4A4WX68, TRPD_CERS5B9KMV1, TRPD_CERSK
Q11HU2, TRPD_CHESBA9WCH7, TRPD_CHLAAB8G5C5, TRPD_CHLAD
Q3APT3, TRPD_CHLCHQ822W6, TRPD_CHLCVQ254S7, TRPD_CHLFF
B3EH38, TRPD_CHLL2Q3B2H3, TRPD_CHLL3B3QM44, TRPD_CHLP8
B3EMT4, TRPD_CHLPBA1BE13, TRPD_CHLPDA4SFZ6, TRPD_CHLPM
B9LEV9, TRPD_CHLSYB3QUY6, TRPD_CHLT3Q8KC17, TRPD_CHLTE
A0M4T1, TRPD_CHRFKQ1QV38, TRPD_CHRI1Q7NW17, TRPD_CHRVO
B5EBU6, TRPD_CITBBA5CS25, TRPD_CLAM3B0REA1, TRPD_CLASE
Q97EF2, TRPD_CLOABA6LU93, TRPD_CLOB8B9E148, TRPD_CLOK1
A5N7N7, TRPD_CLOK5Q47YC2, TRPD_COLP3C3PKY4, TRPD_CORA7
Q6NEC1, TRPD_CORDIQ8FLJ8, TRPD_COREFA4QI74, TRPD_CORGB
P06559, TRPD_CORGLQ4JWC7, TRPD_CORJKQ1LIH4, TRPD_CUPMC
Q0K6I1, TRPD_CUPNHQ46WU8, TRPD_CUPPJQ11PY2, TRPD_CYTH3
Q47AC6, TRPD_DECARQ3Z6G6, TRPD_DEHM1Q3ZZ15, TRPD_DEHMC
Q1IZP8, TRPD_DEIGDQ9RTJ5, TRPD_DEIRAA9BS05, TRPD_DELAS
B8FA41, TRPD_DESALB1I3Z8, TRPD_DESAPB8FVH5, TRPD_DESHD
Q24SK4, TRPD_DESHYA8ZZX1, TRPD_DESOHQ6AMS5, TRPD_DESPS
A4J146, TRPD_DESRMB5YD05, TRPD_DICT6B8DZP4, TRPD_DICTD
A8LMJ6, TRPD_DINSHA4XZC6, TRPD_ECTM1B1GZB9, TRPD_ENDTX
B2VKT4, TRPD_ERWT9Q2NA97, TRPD_ERYLHB1YLS1, TRPD_EXIS2
A5FA70, TRPD_FLAJ1A6GWZ4, TRPD_FLAPJQ0RFI3, TRPD_FRAAA
B0TWF2, TRPD_FRAP2A7NF00, TRPD_FRATFB2SEF6, TRPD_FRATM
A0Q8R1, TRPD_FRATNQ0BJW6, TRPD_FRATOA4J0E5, TRPD_FRATW
B9M5M2, TRPD_GEODFQ5KXU8, TRPD_GEOKAQ39SQ6, TRPD_GEOMG
Q9X6J5, TRPD_GEOSEQ74AH4, TRPD_GEOSLC6DYM5, TRPD_GEOSM
C5D3D7, TRPD_GEOSWA4IQ85, TRPD_GEOTNA5GES2, TRPD_GEOUR
B8F815, TRPD_GLAP5Q7NGU2, TRPD_GLOVIQ5FNM7, TRPD_GLUOX
Q0BTY4, TRPD_GRABCQ4QKA1, TRPD_HAEI8A5UBZ6, TRPD_HAEIE
A5UEN6, TRPD_HAEIGP43858, TRPD_HAEINQ2S999, TRPD_HAHCH
Q9KCB3, TRPD_HALH5A1WYT2, TRPD_HALHLB9LQ96, TRPD_HALLT
Q5V211, TRPD_HALMAB0R622, TRPD_HALS3Q9HPG3, TRPD_HALSA
P52562, TRPD_HALVDQ18FI8, TRPD_HALWDQ17ZP2, TRPD_HELAH
B6JNC0, TRPD_HELP2B5Z8S5, TRPD_HELPGQ1CRX3, TRPD_HELPH
Q9ZJU7, TRPD_HELPJB2UV44, TRPD_HELPSP56737, TRPD_HELPY
A9B148, TRPD_HERA2A4G1P5, TRPD_HERARB0UU36, TRPD_HISS2
Q31J09, TRPD_HYDCUQ0C1A1, TRPD_HYPNAQ5QX82, TRPD_IDILO
A8ACG6, TRPD_IGNH4A6SUH6, TRPD_JANMAQ28R66, TRPD_JANSC
Q1IJR5, TRPD_KORVEP17170, TRPD_LACCAB3W6W9, TRPD_LACCB
C4Z111, TRPD_LACE2Q02000, TRPD_LACLAA2RK17, TRPD_LACLM
Q02YA8, TRPD_LACLSQ03CY0, TRPD_LACP3A9KL44, TRPD_LACP7
Q88WI3, TRPD_LACPLC1D7P3, TRPD_LARHHQ5X6R9, TRPD_LEGPA
A5IG81, TRPD_LEGPCQ5ZX98, TRPD_LEGPHQ5WY74, TRPD_LEGPL
Q6AFI7, TRPD_LEIXXQ04R23, TRPD_LEPBJQ04ZD2, TRPD_LEPBL
B1Y7I3, TRPD_LEPCPQ72PD0, TRPD_LEPICQ8F708, TRPD_LEPIN
Q03WZ9, TRPD_LEUMMQ92B78, TRPD_LISINC1KVS8, TRPD_LISMC
Q71Z37, TRPD_LISMFB8DHB1, TRPD_LISMHQ8Y6Q3, TRPD_LISMO
A0AJ83, TRPD_LISW6Q65TF2, TRPD_MANSMQ0APU5, TRPD_MARMM
A6VU64, TRPD_MARMSA1U6H0, TRPD_MARN8C6C1D5, TRPD_MARSD
A6UW21, TRPD_META3Q8TLP5, TRPD_METACA7I4T7, TRPD_METB6
Q465F3, TRPD_METBFQ12TL1, TRPD_METBUB7KUV9, TRPD_METC4
Q604F8, TRPD_METCAA9W900, TRPD_METEPQ1GYF5, TRPD_METFK
Q2FKX5, TRPD_METHJQ57686, TRPD_METJAQ8TXJ5, TRPD_METKA
A2STA7, TRPD_METLZA4FXH2, TRPD_METM5A9AAU1, TRPD_METM6
A6VFU3, TRPD_METM7Q8PT97, TRPD_METMAA3CRK8, TRPD_METMJ
Q6LYI4, TRPD_METMPB8IP99, TRPD_METNOB1Z9R9, TRPD_METPB
B8GJ30, TRPD_METPEA2SLH5, TRPD_METPPB1M5Q2, TRPD_METRJ
A5UMC1, TRPD_METS3B0U7Z5, TRPD_METS4A4YHE2, TRPD_METS5
B8EJS2, TRPD_METSBQ2NFE4, TRPD_METSTO27698, TRPD_METTH
P26925, TRPD_METTMA6UP19, TRPD_METVSQ2RIT6, TRPD_MOOTA
P66993, TRPD_MYCBOA1KKN4, TRPD_MYCBPC1AQA7, TRPD_MYCBT
A4TBH5, TRPD_MYCGIB8ZQM2, TRPD_MYCLBO69581, TRPD_MYCLE
B2HGW0, TRPD_MYCMMQ73YM4, TRPD_MYCPAA0R048, TRPD_MYCS2
A3Q1Q2, TRPD_MYCSJA1UI88, TRPD_MYCSKQ1B6T7, TRPD_MYCSS
A5U4M0, TRPD_MYCTAP9WFX4, TRPD_MYCTOP9WFX5, TRPD_MYCTU
A0PTM6, TRPD_MYCUAA1TB00, TRPD_MYCVPQ1CZH6, TRPD_MYXXD
Q3IQ38, TRPD_NATPDQ5F7H5, TRPD_NEIG1A9M4G6, TRPD_NEIM0
P66994, TRPD_NEIMAP66995, TRPD_NEIMBA1KTN4, TRPD_NEIMF
Q0AJP9, TRPD_NITECQ82Y74, TRPD_NITEUQ1QMJ8, TRPD_NITHX
A9A298, TRPD_NITMSQ2Y5W9, TRPD_NITMUQ3J897, TRPD_NITOC
B8DM45, TRPD_NITV9Q3SRJ4, TRPD_NITWNQ5YZ21, TRPD_NOCFA
A1SLE8, TRPD_NOCSJQ2G6R1, TRPD_NOVADQ8ESU1, TRPD_OCEIH
Q30VM1, TRPD_OLEA2A1R6T5, TRPD_PAEATA1TJQ1, TRPD_PARC0
A1B3Y5, TRPD_PARDPA7HXZ5, TRPD_PARL1Q2W3A9, TRPD_PARM1
Q7TTV4, TRPD_PARMWB2JHI7, TRPD_PARP8Q13TW5, TRPD_PARXL
P57856, TRPD_PASMUQ6D4U2, TRPD_PECASP12320, TRPD_PECCA
C6DGZ7, TRPD_PECCPB4SE13, TRPD_PELPBA1ALX3, TRPD_PELPD
A5D1S5, TRPD_PELTSQ4FM53, TRPD_PELUBC0QR68, TRPD_PERMH
A9BHQ6, TRPD_PETMOB4RBX4, TRPD_PHEZHQ7N488, TRPD_PHOLL
Q6LPA6, TRPD_PHOPRA6L7M8, TRPD_PHOV8Q6L273, TRPD_PICTO
A4SV53, TRPD_POLAQB1XSZ2, TRPD_POLNSQ123F3, TRPD_POLSJ
P70936, TRPD_PRIM1B4S5K5, TRPD_PROA2A3PCQ4, TRPD_PROM0
A2C1X5, TRPD_PROM1A8G4M3, TRPD_PROM2A9B9W1, TRPD_PROM4
A2BWT1, TRPD_PROM5Q31B38, TRPD_PROM9Q7VCJ6, TRPD_PROMA
B4EWH5, TRPD_PROMHQ7TV05, TRPD_PROMMQ7TU90, TRPD_PROMP
A2BQY1, TRPD_PROMSQ46L78, TRPD_PROMTQ48NP8, TRPD_PSE14
Q15RZ7, TRPD_PSEA6B7V608, TRPD_PSEA8Q02TB6, TRPD_PSEAB
P20574, TRPD_PSEAEQ1IG00, TRPD_PSEE4Q4K502, TRPD_PSEF5
C3K308, TRPD_PSEFSA5VXL4, TRPD_PSEP1A6UZF1, TRPD_PSEP7
Q3K5V3, TRPD_PSEPFB0KJB2, TRPD_PSEPGQ88QR7, TRPD_PSEPK
P20575, TRPD_PSEPUB1JE35, TRPD_PSEPWQ88A04, TRPD_PSESM
Q3IKY4, TRPD_PSET1Q4ZML2, TRPD_PSEU2A1STT2, TRPD_PSYIN
A5WFZ6, TRPD_PSYWFQ9V1G4, TRPD_PYRABQ8ZV45, TRPD_PYRAE
A4WKR0, TRPD_PYRARA3MVG6, TRPD_PYRCJQ8U089, TRPD_PYRFU
A1RVT0, TRPD_PYRILB2UDK8, TRPD_RALPJB3Q0L2, TRPD_RHIE6
Q2K880, TRPD_RHIECQ1MGE2, TRPD_RHIJ3Q98ME4, TRPD_RHILO
B5ZPY6, TRPD_RHILWQ92PS0, TRPD_RHIMEB9JFD7, TRPD_RHIR8
Q7UYS5, TRPD_RHOBAQ0SHN1, TRPD_RHOJRC1AU95, TRPD_RHOOB
Q2IWB1, TRPD_RHOP2Q07NF5, TRPD_RHOP5Q6N5T0, TRPD_RHOPA
Q215B8, TRPD_RHOPBQ136D3, TRPD_RHOPSB3Q6M8, TRPD_RHOPT
Q2RT49, TRPD_RHORTB7JX56, TRPD_RIPO1A7NL64, TRPD_ROSCS
Q163Y0, TRPD_ROSDOA5UT95, TRPD_ROSS1Q1AU89, TRPD_RUBXD
Q5LRH8, TRPD_RUEPOQ1GHJ3, TRPD_RUESTB8I0U9, TRPD_RUMCH
A1AVF1, TRPD_RUTMCQ21MR4, TRPD_SACD2A4FAC5, TRPD_SACEN
C3NHL1, TRPD_SACI1C3MPW2, TRPD_SACI2C3N5I8, TRPD_SACI3
C3MV89, TRPD_SACI4C4KH54, TRPD_SACI6C3NE52, TRPD_SACI7
P50384, TRPD_SACS2A8LYC4, TRPD_SALAIQ2S1Z6, TRPD_SALRD
A4X9Z2, TRPD_SALTOO60122, TRPD_SCHPOP12321, TRPD_SERMA
A8GF80, TRPD_SERP5A1S7I0, TRPD_SHEAMA3D628, TRPD_SHEB5
A6WPW9, TRPD_SHEB8A9KTR5, TRPD_SHEB9Q12LE4, TRPD_SHEDO
Q084N6, TRPD_SHEFNA3QF71, TRPD_SHELPQ8ECV2, TRPD_SHEON
A4Y843, TRPD_SHEPCA0KVD3, TRPD_SHESAQ0HK79, TRPD_SHESM
Q0HWI1, TRPD_SHESRA1RIE5, TRPD_SHESWQ5WGS4, TRPD_SHOC1
C3MCF3, TRPD_SINFNA6U9C4, TRPD_SINMWQ2NT50, TRPD_SODGM
Q021N5, TRPD_SOLUEA9F0C1, TRPD_SORC5Q1GUW8, TRPD_SPHAL
A7X232, TRPD_STAA1A6U1J1, TRPD_STAA2Q2FH67, TRPD_STAA3
Q2FYR7, TRPD_STAA8A5ISQ1, TRPD_STAA9Q9RL77, TRPD_STAAC
A6QGS1, TRPD_STAAEP66996, TRPD_STAAMP66997, TRPD_STAAN
Q6G9J0, TRPD_STAASP66998, TRPD_STAAWB9DP50, TRPD_STACT
Q5HPH3, TRPD_STAEQQ8CSN6, TRPD_STAESQ4L676, TRPD_STAHJ
Q49XH5, TRPD_STAS1Q82AK1, TRPD_STRAWA8AW02, TRPD_STRGC
B1VZR5, TRPD_STRGGB4SLE9, TRPD_STRM5B2FKL2, TRPD_STRMK
Q8DVF6, TRPD_STRMUQ04IY6, TRPD_STRP2B5E7M6, TRPD_STRP4
C1C969, TRPD_STRP7B1I7T0, TRPD_STRPIB8ZN62, TRPD_STRPJ
P66999, TRPD_STRPNB2ISS4, TRPD_STRPSP67000, TRPD_STRR6
A3CLL8, TRPD_STRSVQ5LYI4, TRPD_STRT1Q5M347, TRPD_STRT2
Q03JB8, TRPD_STRTDC1CG45, TRPD_STRZJC1CMD6, TRPD_STRZP
C1CT54, TRPD_STRZTA4VHK0, TRPD_STUS1Q4J8X7, TRPD_SULAC
B2V751, TRPD_SULSYQ971Z7, TRPD_SULTOQ67PJ9, TRPD_SYMTH
Q3A6L6, TRPD_SYNC1Q31LB6, TRPD_SYNE7A0LJ59, TRPD_SYNFM
Q2JWL5, TRPD_SYNJAQ2JQ65, TRPD_SYNJBQ5N0L1, TRPD_SYNP6
A5GKM1, TRPD_SYNPWA5GTM6, TRPD_SYNR3Q0I9N0, TRPD_SYNS3
Q3AXD5, TRPD_SYNS9Q0B006, TRPD_SYNWWP73617, TRPD_SYNY3
C5BPA3, TRPD_TERTTQ9HK06, TRPD_THEACQ47R55, TRPD_THEFY
Q9YGB4, TRPD_THEKOB0K8T3, TRPD_THEP3B0K2U2, TRPD_THEPX
B9KXB8, TRPD_THERPQ72HJ6, TRPD_THET2Q5SH88, TRPD_THET8
P83827, TRPD_THETHQ8DI76, TRPD_THEVBQ979V5, TRPD_THEVO
Q3SGS1, TRPD_THIDAB8GNI1, TRPD_THISHC4LC91, TRPD_TOLAT
Q112P2, TRPD_TRIEIB3E5V8, TRPD_TRIL1Q3M4T0, TRPD_TRIV2
A1WH74, TRPD_VEREIA5CXR3, TRPD_VESOHA7MRZ7, TRPD_VIBC1
A5F210, TRPD_VIBC3Q9KST4, TRPD_VIBCHP22096, TRPD_VIBPA
Q8D8B4, TRPD_VIBVUQ7MM54, TRPD_VIBVYQ8PQ48, TRPD_XANAC
Q4UZF9, TRPD_XANC8B0RMZ8, TRPD_XANCBQ8PD71, TRPD_XANCP
Q3BYB6, TRPD_XANE5Q2NYD6, TRPD_XANOMB2SL02, TRPD_XANOP
A7INK3, TRPD_XANP2B2I6S4, TRPD_XYLF2Q9PGT6, TRPD_XYLFA
B0U1N9, TRPD_XYLFMQ87EX3, TRPD_XYLFTP07285, TRPD_YEAST
A7FI31, TRPD_YERP3Q1C7P0, TRPD_YERPAB2K3W4, TRPD_YERPB
Q8ZEG7, TRPD_YERPEQ1CJ26, TRPD_YERPNA4TJ65, TRPD_YERPP
Q66AK2, TRPD_YERPSB1JKS0, TRPD_YERPYP00904, TRPGD_ECOLI
P00905, TRPGD_SALTYQ08654, TRPGD_THEMAP00906, TRPG_SHIDY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.2.-
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