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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 188.8.131.52
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|Nicotinamide adenine dinucleotide glycohydrolase.|
|Nicotinamide adenine dinucleotide nucleosidase.|
|NAD(+) + H(2)O <=> ADP-D-ribose + nicotinamide|
- This enzyme catalyzes the hydrolysis of NAD(+), without associated
ADP-ribosyl cyclase activity (unlike the metazoan enzyme EC 184.108.40.206,
bifunctional ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase).
- The enzyme from Group A streptococci has been implicated in the
pathogenesis of diseases such as streptococcal toxic shock-like
syndrome (STSS) and necrotizing fasciitis.
- The enzyme from the venom of the snake Agkistrodon acutus also
catalyzes EC 220.127.116.11.
|PRIAM enzyme-specific profiles||18.104.22.168|
|KEGG Ligand Database for Enzyme Nomenclature||22.214.171.124|
|IUBMB Enzyme Nomenclature||126.96.36.199|
|MEDLINE||Find literature relating to 188.8.131.52|
entries corresponding to 3.2.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-