A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 4.1.1.107
| Accepted Name |
|---|
| 3,4-dihydroxyphenylacetaldehyde synthase.
|
| Reaction catalysed |
|---|
| L-dopa + O(2) + H(2)O <=> 3,4-dihydroxyphenylacetaldehyde + CO(2) + NH(3) + H(2)O(2) |
| Cofactor(s) |
|---|
| Pyridoxal 5'-phosphate.
|
| Comment(s) |
|---|
- The enzyme, isolated from the mosquito Aedes aegypti, catalyzes the
production of 3,4-dihydroxylphenylacetaldehyde directly from L-dopa.
- Dopamine is not formed as an intermediate (cf. EC 4.1.1.28).
- The enzyme is specific for L-dopa and does not react with other
aromatic amino acids with the exception of a low activity with alpha-
methyl-L-dopa.
|
| Cross-references |
|---|
| BRENDA | 4.1.1.107 |
| EC2PDB | 4.1.1.107 |
| ExplorEnz | 4.1.1.107 |
| PRIAM enzyme-specific profiles | 4.1.1.107 |
| KEGG Ligand Database for Enzyme Nomenclature | 4.1.1.107 |
| IUBMB Enzyme Nomenclature | 4.1.1.107 |
| IntEnz | 4.1.1.107 |
| MEDLINE | Find literature relating to 4.1.1.107 |
| MetaCyc | 4.1.1.107 |
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All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 4.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-