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ENZYME entry: EC 4.1.1.86

Accepted Name
Diaminobutyrate decarboxylase.
Alternative Name(s)
DABA DC.
L-2,4-diaminobutanoate carboxy-lyase.
L-2,4-diaminobutyrate decarboxylase.
Reaction catalysed
L-2,4-diaminobutanoate <=> propane-1,3-diamine + CO(2)
Cofactor(s)
Divalent cation; Pyridoxal 5'-phosphate.
Comment(s)
  • N(4)-acetyl-L-2,4-diaminobutanoate, 2,3-diaminopropanoate, ornithine and lysine are not substrates.
  • In Acinetobacter baumannii it is cotranscribed with the neighboring dat gene that encodes EC 2.6.1.76, which can supply the substrate for the decarboxylase.
Cross-references
BRENDA4.1.1.86
EC2PDB4.1.1.86
ExplorEnz4.1.1.86
PRIAM enzyme-specific profiles4.1.1.86
KEGG Ligand Database for Enzyme Nomenclature4.1.1.86
IUBMB Enzyme Nomenclature4.1.1.86
IntEnz4.1.1.86
MEDLINEFind literature relating to 4.1.1.86
MetaCyc4.1.1.86
UniProtKB/Swiss-Prot
Q43908, DDC_ACIBA;  P71362, DDC_HAEIN;  Q9Z3R1, RHBB_RHIME;  

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