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ENZYME

ENZYME entry: EC 4.1.1.94

PURL: https://purl.expasy.org/enzyme/EC/4.1.1.94
Accepted Name
ethylmalonyl-CoA decarboxylase
Reaction catalysed
(2S)-ethylmalonyl-CoA + H(+) = butanoyl-CoA + CO2
Comment(s)
  • The enzyme, which exists in all vertebrates, decarboxylates ethylmalonyl-CoA, a potentially toxic compound that is formed in low amounts by the activity of EC 6.4.1.2 and EC 6.4.1.3.
  • It prefers the S isomer, and can decarboxylate (R)-ethylmalonyl-CoA with lower efficiency. cf. EC 4.1.1.41.
  • Formerly EC 4.1.1.n2.
Cross-references
BRENDA4.1.1.94
EC2PDB4.1.1.94
ExplorEnz4.1.1.94
KEGG Ligand Database for Enzyme Nomenclature4.1.1.94
IUBMB Enzyme Nomenclature4.1.1.94
MEDLINEFind literature relating to 4.1.1.94
MetaCyc4.1.1.94
Rhea expert-curated reactions4.1.1.94
UniProtKB/Swiss-Prot
Q2HJD5, ECHD1_BOVINF1NB38, ECHD1_CHICKF1R6N4, ECHD1_DANRE
Q9NTX5, ECHD1_HUMANQ9D9V3, ECHD1_MOUSEQ5R4W0, ECHD1_PONAB
Q6AYG5, ECHD1_RATQ5HZQ8, ECHD1_XENLAQ28C91, ECHD1_XENTR

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-