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ENZYME entry: EC 4.1.2.14

Accepted Name
2-dehydro-3-deoxy-phosphogluconate aldolase.
Alternative Name(s)
2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate- lyase.
2-keto-3-deoxy-6-phosphogluconate aldolase.
KDPG-aldolase.
phospho-2-dehydro-3-deoxygluconate aldolase.
phospho-2-keto-3-deoxygluconate aldolase.
Reaction catalysed
2-dehydro-3-deoxy-6-phospho-D-gluconate <=> D-glyceraldehyde 3-phosphate + pyruvate
Comment(s)
  • The enzyme shows no activity with 2-dehydro-3-deoxy-6-phosphate-D- galactonate (cf. EC 4.1.2.55).
  • Also acts on 2-oxobutanoate.
Cross-references
BRENDA4.1.2.14
EC2PDB4.1.2.14
ExplorEnz4.1.2.14
PRIAM enzyme-specific profiles4.1.2.14
KEGG Ligand Database for Enzyme Nomenclature4.1.2.14
IUBMB Enzyme Nomenclature4.1.2.14
IntEnz4.1.2.14
MEDLINEFind literature relating to 4.1.2.14
MetaCyc4.1.2.14
Rhea expert-curated reactions4.1.2.14
UniProtKB/Swiss-Prot
Q15X88, ALKD_PSEA6;  O68283, ALKD_PSEAE;  P00885, ALKD_PSEPU;  
P50846, ALKH_BACSU;  P38448, ALKH_DICD3;  P0A957, ALKH_ECO57;  
P0A956, ALKH_ECOL6;  P0A955, ALKH_ECOLI;  P44480, ALKH_HAEIN;  
P0A958, ALKH_SHIFL;  O83578, ALKH_TREPA;  Q00384, ALKH_ZYMMO;  
D0ZLR2, DGAF_SALT1;  Q6KZI8, KDGA_PICTO;  Q704D1, KDGA_THETE;  

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