Home  |  Contact

ENZYME entry: EC 4.1.2.60

Accepted Name
Dihydroneopterin triphosphate aldolase.
Reaction catalysed
7,8-dihydroneopterin 3'-triphosphate <=> 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde triphosphate
Comment(s)
  • The enzyme, which participates in a pathway for folate biosynthesis, is found in the Stramenopiles, a large group that includes oomycetes, various microalgae and brown algae, as well as in several bacterial phyla.
  • It provides a bypass mechanism compensating for the lack of EC 4.1.2.25.
  • In the malaria parasite Plasmodium falciparum the enzyme is bifunctional and also catalyzes the activity of EC 4.2.3.12.
  • Cf. EC 4.1.2.59.
Cross-references
BRENDA4.1.2.60
EC2PDB4.1.2.60
ExplorEnz4.1.2.60
PRIAM enzyme-specific profiles4.1.2.60
KEGG Ligand Database for Enzyme Nomenclature4.1.2.60
IUBMB Enzyme Nomenclature4.1.2.60
IntEnz4.1.2.60
MEDLINEFind literature relating to 4.1.2.60
MetaCyc4.1.2.60

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-