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ENZYME entry: EC 4.1.2.n2

Accepted Name
2-hydroxyacyl-CoA lyase.
Alternative Name(s)
2-HPCL.
2-hydroxyphytanoyl-CoA lyase.
Reaction catalysed
2-hydroxyphytanoyl-CoA <=> formyl-CoA + pristanal
Cofactor(s)
Mg(2+); Thiamine diphosphate.
Comment(s)
This peroxisomal enzyme, found in animals, is involved in the alpha- oxidation of 3-methyl-branched fatty acids like phytanic acid and the shortening of 2-hydroxy long-chain fatty acids.
Cross-references
UniProtKB/Swiss-Prot
Q54DA9, HACL1_DICDI;  Q9UJ83, HACL1_HUMAN;  Q9QXE0, HACL1_MOUSE;  
Q8CHM7, HACL1_RAT;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
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