ENZYME entry: EC 4.2.1.111
| Accepted Name |
|---|
| 1,5-anhydro-D-fructose dehydratase.
|
| Alternative Name(s) |
|---|
| 1,5-anhydro-D-arabino-hex-2-ulose dehydratase. |
| 1,5-anhydro-D-fructose 4-dehydratase. |
| 1,5-anhydro-D-fructose hydrolyase. |
| AF dehydratase. |
| AFDH. |
| Reaction catalysed |
|---|
| 1,5-anhydro-D-fructose <=> ascopyrone M + H2O |
| Comment(s) |
|---|
- Catalyzes one of the steps in the anhydrofructose pathway, which
leads to the degradation of glycogen and starch via 1,5-anhydro-D-
fructose.
- The other enzymes involved in this pathway are EC 4.2.1.110,
EC 4.2.2.13 and EC 5.3.2.7.
- Unlike EC 4.2.1.110 the enzyme is specific for 1,5-anhydro-D-fructose
as substrate and shows no activity toward aldose-2-uloses such as
2-dehydroglucose; in addition, it is inhibited by its end-product
ascopyrone M and it cannot convert the end-product ascopyrone M into
microthecin, as can EC 4.2.1.110.
|
| Cross-references |
|---|
| BRENDA | 4.2.1.111 |
| EC2PDB | 4.2.1.111 |
| ExplorEnz | 4.2.1.111 |
| PRIAM enzyme-specific profiles | 4.2.1.111 |
| KEGG Ligand Database for Enzyme Nomenclature | 4.2.1.111 |
| IUBMB Enzyme Nomenclature | 4.2.1.111 |
| IntEnz | 4.2.1.111 |
| MEDLINE | Find literature relating to 4.2.1.111 |
| MetaCyc | 4.2.1.111 |
| Rhea expert-curated reactions | 4.2.1.111 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 4.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-