ENZYME entry: EC 4.2.1.79
Accepted Name |
2-methylcitrate dehydratase.
|
Alternative Name(s) |
2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase. |
2-methylcitrate hydro-lyase. |
Reaction catalysed |
(2S,3S)-2-methylcitrate <=> 2-methyl-cis-aconitate + H2O |
Comment(s) |
- Specific for (2S,3S)-methylcitrate, showing no activity with (2R,3S)-
methylcitrate.
- Can also use cis-aconitate as a substrate but more slowly.
- Both this enzyme and EC 4.2.1.3 are required to complete the
isomerization of (2S,3S)-methylcitrate to (2R,3S)-2-methylisocitrate.
|
Cross-references |
BRENDA | 4.2.1.79 |
EC2PDB | 4.2.1.79 |
ExplorEnz | 4.2.1.79 |
PRIAM enzyme-specific profiles | 4.2.1.79 |
KEGG Ligand Database for Enzyme Nomenclature | 4.2.1.79 |
IUBMB Enzyme Nomenclature | 4.2.1.79 |
IntEnz | 4.2.1.79 |
MEDLINE | Find literature relating to 4.2.1.79 |
MetaCyc | 4.2.1.79 |
Rhea expert-curated reactions | 4.2.1.79 |
UniProtKB/Swiss-Prot |
Q8NSH9, PRPD1_CORGL; | Q8NSL3, PRPD2_CORGL; | Q937N6, PRPD_CUPNE; |
Q54IJ0, PRPD_DICDI; | Q8X693, PRPD_ECO57; | P77243, PRPD_ECOLI; |
H8F0D6, PRPD_MYCTE; | O06582, PRPD_MYCTU; | Q8Z903, PRPD_SALTI; |
P74840, PRPD_SALTY; | Q6C354, PRPD_YARLI; | Q12428, PRPD_YEAST; |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 4.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-