Accepted Name |
(-)-alpha-pinene synthase
|
Alternative Name(s) |
(-)-alpha-pinene/(-)-camphene synthase |
(-)-alpha-pinene cyclase |
Reaction catalysed |
(2E)-geranyl diphosphate <=> (1S,5S)-alpha-pinene + diphosphate |
Comment(s) |
- Cyclase II of Salvia officinalis (sage) gives about equal parts (-)-
alpha-pinene, (-)-beta-pinene and (-)-camphene, plus traces of other
monoterpenoids.
- (3S)-linalyl diphosphate can also be used by the enzyme in preference
to (3R)-linalyl diphosphate.
- The 4-pro-S hydrogen of geranyl diphosphate is lost.
- The enzyme from Abies grandis (grand fir) gives roughly equal parts
(-)-alpha-pinene and (-)-beta-pinene.
- However the clone ag11 gave 35% (-)-limonene, 24% (-)-alpha-pinene
and 20% (-)-beta-phellandrene.
- Synthase I from Pinus taeda (loblolly pine) produces (-)-alpha-pinene
with traces of (-)-beta-pinene.
- The enzyme from Picea sitchensis (Sika spruce) forms 70% (-)-alpha-
pinene and 30% (-)-beta-pinene.
- The recombinant PmeTPS1 enzyme from Pseudotsuga menziesii (Douglas
fir) gave roughly equal proportions of (-)-alpha-pinene and (-)-
camphene plus traces of other monoterpenoids.
- See also EC 4.2.3.120, EC 4.2.3.117, EC 4.2.3.16 and EC 4.2.3.52.
- Formerly EC 4.1.99.8, EC 4.2.3.14 and EC 4.2.3.n7.
|
Cross-references |
BRENDA | 4.2.3.119 |
EC2PDB | 4.2.3.119 |
ExplorEnz | 4.2.3.119 |
PRIAM enzyme-specific profiles | 4.2.3.119 |
KEGG Ligand Database for Enzyme Nomenclature | 4.2.3.119 |
IUBMB Enzyme Nomenclature | 4.2.3.119 |
IntEnz | 4.2.3.119 |
MEDLINE | Find literature relating to 4.2.3.119 |
MetaCyc | 4.2.3.119 |
Rhea expert-curated reactions | 4.2.3.119 |
UniProtKB/Swiss-Prot |
R9QMY8, CAMPS_PINCO | F2XF95, PINS1_PICGL | F2XFA8, PINS1_PICSI |
F2XF96, PINS2_PICGL | Q6XDB5, PINS2_PICSI | O23945, PINS_FRAVE |
Q84KL6, PT1_PINTA | R9QMY9, SAPN1_PINBN | R9QMR3, SAPN1_PINCO |
R9QMR0, SBPN1_PINBN | R9QMQ9, SBPN1_PINCO | R9QMW5, SBPN2_PINBN |
R9QMW1, SPIN1_PINBN | O24475, TPSD3_ABIGR | Q9M7C9, TPSDB_ABIGR |
|
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