ENZYME

A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_09. Read more about EC 7 here.

ENZYME entry: EC 4.2.3.120

Accepted Name

(-)-beta-pinene synthase.

Alternative Name(s)

(-)-(1S,5S)-pinene synthase.

Beta-geraniolene synthase.

Reaction catalysed

Geranyl diphosphate <=> (-)-beta-pinene + diphosphate

Comment(s)

Cyclase II of Salvia officinalis (sage) produces about equal parts (-)-alpha-pinene, (-)-beta-pinene and (-)-camphene, plus traces of other monoterpenoids.
The enzyme can also use (3S)-Linalyl diphosphate (preferred to (3R)- linalyl diphosphate).
The enzyme from Abies grandis (grand fir) produces roughly equal parts of (-)-alpha-pinene and (-)-beta-pinene.
Cyclase IV from Pinus contorta (lodgepole pine) produces 63% (-)- beta-pinene, 26% 3-carene, and traces of alpha-pinene.
Synthase III from Pinus taeda (loblolly pine) forms (-)-beta-pinene with traces of alpha-pinene.
A cloned enzyme from Artemisia annua (sweet wormwood) gave (-)-beta- pinene with traces of (-)-alpha-pinene.
The enzyme from Picea sitchensis (Sika spruce) forms 30% (-)-beta- pinene and 70% (-)-alpha-pinene.
See also EC 4.2.3.119, EC 4.2.3.117 and EC 4.2.3.107.
Formerly EC 4.1.99.8 and EC 4.2.3.14.

Cross-references

BRENDA

EC2PDB

ExplorEnz

PRIAM enzyme-specific profiles

KEGG Ligand Database for Enzyme Nomenclature

IUBMB Enzyme Nomenclature