ENZYME entry: EC 4.3.1.13
| Accepted Name |
|---|
| Carbamoyl-serine ammonia-lyase.
|
| Alternative Name(s) |
|---|
| O-carbamoyl-L-serine deaminase. |
| Reaction catalysed |
|---|
| O-carbamoyl-L-serine + H(2)O <=> pyruvate + 2 NH(3) + CO(2) |
| Cofactor(s) |
|---|
| Pyridoxal 5'-phosphate.
|
| Comment(s) |
|---|
- The enzyme cleaves a carbon-oxygen bond, releasing CO(2), ammonia,
and an unstable enamine product that tautomerizes to an imine form,
which undergoes a hydrolytic deamination to form pyruvate and a
second ammonia molecule.
- The latter reaction, which can occur spontaneously, can also be
catalyzed by EC 3.5.99.10.
|
| Cross-references |
|---|
| BRENDA | 4.3.1.13 |
| EC2PDB | 4.3.1.13 |
| ExplorEnz | 4.3.1.13 |
| PRIAM enzyme-specific profiles | 4.3.1.13 |
| KEGG Ligand Database for Enzyme Nomenclature | 4.3.1.13 |
| IUBMB Enzyme Nomenclature | 4.3.1.13 |
| IntEnz | 4.3.1.13 |
| MEDLINE | Find literature relating to 4.3.1.13 |
| MetaCyc | 4.3.1.13 |
| Rhea expert-curated reactions | 4.3.1.13 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 4.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-