ENZYME entry: EC 4.3.1.13

PURL: https://purl.expasy.org/enzyme/EC/4.3.1.13

Accepted Name
carbamoyl-serine ammonia-lyase
Alternative Name(s)
O-carbamoyl-L-serine deaminase
Reaction catalysed
O-carbamoyl-L-serine + H2O + H(+) = pyruvate + 2 NH4(+) + CO2
Comment(s)
The enzyme cleaves a carbon-oxygen bond, releasing CO2, ammonia, and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and a second ammonia molecule. The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.
Cross-references
BRENDA	4.3.1.13
EC2PDB	4.3.1.13
ExplorEnz	4.3.1.13
KEGG Ligand Database for Enzyme Nomenclature	4.3.1.13
IUBMB Enzyme Nomenclature	4.3.1.13
MEDLINE	Find literature relating to 4.3.1.13
MetaCyc	4.3.1.13
Rhea expert-curated reactions	4.3.1.13

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-