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ENZYME

ENZYME entry: EC 4.3.1.13

Accepted Name
carbamoyl-serine ammonia-lyase
Alternative Name(s)
O-carbamoyl-L-serine deaminase
Reaction catalysed
H(+) + H2O + O-carbamoyl-L-serine = CO2 + 2 NH4(+) + pyruvate
Comment(s)
  • The enzyme cleaves a carbon-oxygen bond, releasing CO2, ammonia, and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and a second ammonia molecule.
  • The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.
Cross-references
BRENDA4.3.1.13
EC2PDB4.3.1.13
ExplorEnz4.3.1.13
PRIAM enzyme-specific profiles4.3.1.13
KEGG Ligand Database for Enzyme Nomenclature4.3.1.13
IUBMB Enzyme Nomenclature4.3.1.13
IntEnz4.3.1.13
MEDLINEFind literature relating to 4.3.1.13
MetaCyc4.3.1.13
Rhea expert-curated reactions4.3.1.13

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-