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ENZYME entry: EC 6.2.1.50

Accepted Name
4-hydroxybenzoate adenylyltransferase FadD22.
Alternative Name(s)
4-hydroxybenzoate adenylase.
Reaction catalysed
ATP + 4-hydroxybenzoate + holo-[4-hydroxyphenylalkanoate synthase] <=> AMP + diphosphate + 4-hydroxybenzoyl-[4-hydroxyphenylalkanoate synthase]
Comment(s)
  • This mycobacterial enzyme participates in the biosynthesis of phenolphthiocerols.
  • Following the substrate's activation by adenylation, it is transferred to an acyl-carrier protein domain within the enzyme, from which it is transferred to EC 2.3.1.261.
  • Formerly EC 2.7.7.98.
Cross-references
BRENDA6.2.1.50
EC2PDB6.2.1.50
ExplorEnz6.2.1.50
PRIAM enzyme-specific profiles6.2.1.50
KEGG Ligand Database for Enzyme Nomenclature6.2.1.50
IUBMB Enzyme Nomenclature6.2.1.50
IntEnz6.2.1.50
MEDLINEFind literature relating to 6.2.1.50
MetaCyc6.2.1.50
UniProtKB/Swiss-Prot
Q7TXK7, FAA22_MYCBO;  B2HIL6, FAA22_MYCMM;  P9WQ60, FAA22_MYCTO;  
P9WQ61, FAA22_MYCTU;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-