| Accepted Name |
|---|
| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase.
|
| Alternative Name(s) |
|---|
| MurF synthetase. |
| UDPacetylmuramoylpentapeptide synthetase. |
| UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase. |
| UDP-MurNAc-pentapeptide synthetase. |
| UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase. |
| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-
alanine ligase. |
| UDP-N-acetylmuramoylalanyl-D-glutamyl-lysine-D-alanyl-D-alanine ligase. |
| UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine
synthetase. |
| UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-
alanyl-D-alanine synthetase. |
| uridine diphosphoacetylmuramoylpentapeptide synthetase. |
| Reaction catalysed |
|---|
| ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysine <=> ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine |
| Comment(s) |
|---|
- Involved with EC 6.3.2.4, EC 6.3.2.7 or EC 6.3.2.13, EC 6.3.2.8 and
EC 6.3.2.9 in the synthesis of a cell-wall peptide.
- Also catalyzes the reaction when the C-terminal residue of the
tripeptide is meso-2,6-diaminoheptanedioate (acylated at its
L-center), linking the D-Ala--D-Ala to the carboxy group of the
L-center.
- Formerly EC 6.3.2.15.
|
| Cross-references |
|---|
| BRENDA | 6.3.2.10 |
| EC2PDB | 6.3.2.10 |
| ExplorEnz | 6.3.2.10 |
| PRIAM enzyme-specific profiles | 6.3.2.10 |
| KEGG Ligand Database for Enzyme Nomenclature | 6.3.2.10 |
| IUBMB Enzyme Nomenclature | 6.3.2.10 |
| IntEnz | 6.3.2.10 |
| MEDLINE | Find literature relating to 6.3.2.10 |
| MetaCyc | 6.3.2.10 |
| Rhea expert-curated reactions | 6.3.2.10 |
| UniProtKB/Swiss-Prot |
| P96613, MURF_BACSU; | Q44777, MURF_BORBU; | P57315, MURF_BUCAI; |
| Q89AQ1, MURF_BUCBP; | P11880, MURF_ECOLI; | P45061, MURF_HAEIN; |
| P0A5L5, MURF_MYCBO; | O69556, MURF_MYCLE; | P9WJL0, MURF_MYCTO; |
| P9WJL1, MURF_MYCTU; | Q92H60, MURF_RICCN; | Q9AKP1, MURF_RICMO; |
| O05953, MURF_RICPR; | O33804, MURF_STRTO; | P45450, MURF_SYNY3; |
| O83401, MURF_TREPA; |
|