ENZYME entry: EC 6.3.2.26
Accepted Name |
N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase.
|
Alternative Name(s) |
ACV synthetase. |
L-alpha-aminoadipyl-cysteinyl-valine synthetase. |
L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase. |
Reaction catalysed |
3 ATP + H2O + L-2-aminoadipate + L-cysteine + L-valine <=> 3 AMP + 3 diphosphate + 3 H(+) + N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine |
Comment(s) |
- The enzyme contains 4'-phosphopantetheine, which may be involved in
the mechanism of the reaction.
- Forms part of the penicillin biosynthesis pathway.
|
Cross-references |
BRENDA | 6.3.2.26 |
EC2PDB | 6.3.2.26 |
ExplorEnz | 6.3.2.26 |
PRIAM enzyme-specific profiles | 6.3.2.26 |
KEGG Ligand Database for Enzyme Nomenclature | 6.3.2.26 |
IUBMB Enzyme Nomenclature | 6.3.2.26 |
IntEnz | 6.3.2.26 |
MEDLINE | Find literature relating to 6.3.2.26 |
MetaCyc | 6.3.2.26 |
Rhea expert-curated reactions | 6.3.2.26 |
UniProtKB/Swiss-Prot |
|
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