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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 220.127.116.11
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|ATP + (R)-4-phosphopantoate + beta-alanine <=> AMP + diphosphate + (R)-4'-phosphopantothenate|
- The conversion of (R)-pantoate to (R)-4'-phosphopantothenate is part
of the pathway leading to biosynthesis of 4'-phosphopantetheine,
an essential cofactor of coenzyme A and acyl-carrier protein.
- In bacteria and eukaryotes this conversion is performed by
condensation with beta-alanine, followed by phosphorylation
(EC 18.104.22.168 and EC 22.214.171.124, respectively).
- In archaea the order of these two steps is reversed,
and phosphorylation precedes condensation with beta-alanine.
- The two archaeal enzymes that catalyze this conversion are
EC 126.96.36.199 and this enzyme.
|PRIAM enzyme-specific profiles||188.8.131.52|
|KEGG Ligand Database for Enzyme Nomenclature||184.108.40.206|
|IUBMB Enzyme Nomenclature||220.127.116.11|
|MEDLINE||Find literature relating to 18.104.22.168|
entries corresponding to 6.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-