Home  |  Contact
Due to maintenance work, this service will be unavailable Mon Feb 13 between 07:00 and 09:30 - CET. Apologies for the inconvenience.

ENZYME entry: EC

Accepted Name
aerobactin synthase.
Reaction catalysed
ATP + N(2)-citryl-N(6)-acetyl-N(6)-hydroxy-L-lysine + N(6)-acetyl-N(6)-hydroxy-L-lysine <=> aerobactin + AMP + diphosphate + H(+)
  • Requires Mg(2+).
  • The enzyme is involved in the biosynthesis of aerobactin, a dihydroxamate siderophore.
  • It belongs to a class of siderophore synthases known as type C nonribosomal peptide synthase-independent synthases (NIS).
  • Type C enzymes are responsible for the formation of amide or ester bonds between a variety of substrates and a prochiral carboxyl group of a citrate molecule that is already linked to a different moiety at its other prochiral carboxyl group.
  • The enzyme is believed to form an adenylate intermediate prior to ligation.
  • Formerly EC
PRIAM enzyme-specific profiles6.3.2.39
KEGG Ligand Database for Enzyme Nomenclature6.3.2.39
IUBMB Enzyme Nomenclature6.3.2.39
MEDLINEFind literature relating to
Rhea expert-curated reactions6.3.2.39

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-