Expasy logo

ENZYME

ENZYME entry: EC 6.3.2.53

PURL: https://purl.expasy.org/enzyme/EC/6.3.2.53
Accepted Name
UDP-N-acetylmuramoyl-L-alanine--L-glutamate ligase
Alternative Name(s)
UDP-MurNAc-L-Ala-L-Glu synthetase
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate synthetase
Reaction catalysed
UDP-N-acetyl-alpha-D-muramoyl-L-alanine + L-glutamate + ATP = UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate + ADP + phosphate + H(+)
Comment(s)
  • The enzyme, characterized from the bacterium Xanthomonas oryzae, catalyzes the ligation of a terminal L-glutamate to UDP-N-acetyl- alpha-D-muramoyl-L-alanine.
  • The combined activity of this enzyme and EC 5.1.1.23 provides an alternative route for incorporating D-glutamate into peptidoglycan, replacing the more common combination of EC 5.1.1.3 and EC 6.3.2.9.
Cross-references
Rhea expert-curated reactions6.3.2.53
ExplorEnz6.3.2.53
IUBMB Enzyme Nomenclature6.3.2.53
UniProtKB/Swiss-Prot
C4RJF7, MURD2_MICS3A4X981, MURD2_SALTOQ8PII9, MURD2_XANC3
Q4UWX9, MURD2_XANC8Q8P775, MURD2_XANCPQ3BR29, MURD2_XANE5
Q2P5V2, MURD2_XANOMQ5H2Y1, MURD2_XANORQ9PEB0, MURD2_XYLFA
Q87EA7, MURD2_XYLFT
BRENDA6.3.2.53
MetaCyc6.3.2.53
KEGG Ligand Database for Enzyme Nomenclature6.3.2.53
EC2PDB6.3.2.53
MEDLINEFind literature relating to 6.3.2.53

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-