ENZYME entry: EC 6.3.2.53
Accepted Name |
UDP-N-acetylmuramoyl-L-alanine--L-glutamate ligase.
|
Alternative Name(s) |
UDP-MurNAc-L-Ala-L-Glu synthetase. |
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate synthetase. |
Reaction catalysed |
ATP + L-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine <=> ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate |
Comment(s) |
- The enzyme, characterized from the bacterium Xanthomonas oryzae,
catalyzes the ligation of a terminal L-glutamate to UDP-N-acetyl-
alpha-D-muramoyl-L-alanine.
- The combined activity of this enzyme and EC 5.1.1.23 provides an
alternative route for incorporating D-glutamate into peptidoglycan,
replacing the more common combination of EC 5.1.1.3 and EC 6.3.2.9.
|
Cross-references |
BRENDA | 6.3.2.53 |
EC2PDB | 6.3.2.53 |
ExplorEnz | 6.3.2.53 |
PRIAM enzyme-specific profiles | 6.3.2.53 |
KEGG Ligand Database for Enzyme Nomenclature | 6.3.2.53 |
IUBMB Enzyme Nomenclature | 6.3.2.53 |
IntEnz | 6.3.2.53 |
MEDLINE | Find literature relating to 6.3.2.53 |
MetaCyc | 6.3.2.53 |
Rhea expert-curated reactions | 6.3.2.53 |
UniProtKB/Swiss-Prot |
C4RJF7, MURD2_MICS3; | A4X981, MURD2_SALTO; | Q8PII9, MURD2_XANAC; |
Q3BR29, MURD2_XANC5; | Q4UWX9, MURD2_XANC8; | Q8P775, MURD2_XANCP; |
Q2P5V2, MURD2_XANOM; | Q5H2Y1, MURD2_XANOR; | Q9PEB0, MURD2_XYLFA; |
Q87EA7, MURD2_XYLFT; |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 6.3.2.-
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