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ENZYME

ENZYME entry: EC 6.3.4.6

PURL: https://purl.expasy.org/enzyme/EC/6.3.4.6
Accepted Name
urea carboxylase
Alternative Name(s)
ATP--urea amidolyase
UALase
UCA
urea amidolyase
urea carboxylase (hydrolyzing)
urease (ATP-hydrolyzing)
Reaction catalysed
urea + hydrogencarbonate + ATP = urea-1-carboxylate + ADP + phosphate + H(+)
Comment(s)
  • A biotinyl-protein.
  • The yeast enzyme (but not that from green algae) is bifunctional (resulting from gene fusion) and also catalyzes the reaction of EC 3.5.1.54, thus bringing about the hydrolysis of urea to CO2 and NH3.
  • cf. EC 6.3.4.26.
  • Formerly EC 3.5.1.45.
Cross-references
BRENDA6.3.4.6
EC2PDB6.3.4.6
ExplorEnz6.3.4.6
KEGG Ligand Database for Enzyme Nomenclature6.3.4.6
IUBMB Enzyme Nomenclature6.3.4.6
MEDLINEFind literature relating to 6.3.4.6
MetaCyc6.3.4.6
Rhea expert-curated reactions6.3.4.6
UniProtKB/Swiss-Prot
A5H0J2, DUR1_LACKLP32528, DUR1_YEASTP38095, LAMA_EMENI

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-