ENZYME entry: EC 1.1.3.17
| Accepted Name |
|---|
| Choline oxidase.
|
| Reaction catalysed |
|---|
| Choline + 2 O(2) + H(2)O <=> betaine + 2 H(2)O(2) |
| Cofactor(s) |
|---|
| FAD.
|
| Comment(s) |
|---|
- In many bacteria, plants and animals, the osmoprotectant betaine is
synthesized using different enzymes to catalyze the conversion of (1)
choline into betaine aldehyde and (2) betaine aldehyde into betaine.
- In plants, the first reaction is catalyzed by EC 1.14.15.7, whereas
in animals and many bacteria, it is catalyzed by either EC 1.1.99.1
or EC 1.1.3.17.
- The enzyme involved in the second step, EC 1.2.1.8, appears to be the
same in those plants, animals and bacteria that use two separate
enzymes.
|
| Cross-references |
|---|
| BRENDA | 1.1.3.17 |
| EC2PDB | 1.1.3.17 |
| ExplorEnz | 1.1.3.17 |
| PRIAM enzyme-specific profiles | 1.1.3.17 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.3.17 |
| IUBMB Enzyme Nomenclature | 1.1.3.17 |
| IntEnz | 1.1.3.17 |
| MEDLINE | Find literature relating to 1.1.3.17 |
| MetaCyc | 1.1.3.17 |
| UniProtKB/Swiss-Prot |
|
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