ENZYME entry: EC 220.127.116.11
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|Choline + O(2) + 2 reduced ferredoxin + 2 H(+) <=> betaine aldehyde hydrate + H(2)O + 2 oxidized ferredoxin|
- Catalyzes the first step of glycine betaine synthesis.
- In many bacteria, plants and animals, the osmoprotectant betaine is
synthesized in two steps: (1) choline to betaine aldehyde and (2)
betaine aldehyde to betaine.
- Different enzymes are involved in the first reaction.
- In plants, the reaction is catalyzed by this enzyme whereas in
animals and many bacteria, it is catalyzed by either membrane-bound
EC 18.104.22.168 or soluble EC 22.214.171.124.
- The enzyme involved in the second step, EC 126.96.36.199, appears to be the
same in plants, animals and bacteria.
- In some bacteria, betaine is synthesized from glycine through the
actions of EC 188.8.131.52 and EC 184.108.40.206.
- Formerly EC 220.127.116.11.
|PRIAM enzyme-specific profiles||18.104.22.168|
|KEGG Ligand Database for Enzyme Nomenclature||22.214.171.124|
|IUBMB Enzyme Nomenclature||126.96.36.199|
|MEDLINE||Find literature relating to 188.8.131.52|
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