Expasy logo

ENZYME

ENZYME entry: EC 1.1.1.393

PURL: https://purl.expasy.org/enzyme/EC/1.1.1.393
Accepted Name
3beta-hydroxycholanate 3-dehydrogenase (NADP(+))
Alternative Name(s)
3beta-hydroxysteroid dehydrogenase
Reaction catalysed
3-oxo-5beta-cholan-24-oate + NADPH + H(+) = isolithocholate + NADP(+)
Comment(s)
  • This bacterial enzyme is involved, along with EC 1.1.1.52 or EC 1.1.1.392, in the modification of secondary bile acids to form 3beta-bile acids (also known as iso-bile acids).
  • The enzyme catalyzes the reaction in the reduction direction in vivo.
  • Also acts on related 3-oxo bile acids. cf. EC 1.1.1.391.
Cross-references
Rhea expert-curated reactions1.1.1.393
ExplorEnz1.1.1.393
IUBMB Enzyme Nomenclature1.1.1.393
UniProtKB/Swiss-Prot
A7AZH2, 3BHDP_MEDG7
BRENDA1.1.1.393
MetaCyc1.1.1.393
KEGG Ligand Database for Enzyme Nomenclature1.1.1.393
EC2PDB1.1.1.393
MEDLINEFind literature relating to 1.1.1.393

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-