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ENZYME

ENZYME entry: EC 2.6.1.81

PURL: https://purl.expasy.org/enzyme/EC/2.6.1.81
Accepted Name
succinylornithine transaminase
Alternative Name(s)
N(2)-succinylornithine 5-aminotransferase
SOAT
succinylornithine aminotransferase
Reaction catalysed
N(2)-succinyl-L-ornithine + 2-oxoglutarate = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate
Comment(s)
  • Also acts on N(2)-acetyl-L-ornithine and L-ornithine, but more slowly.
  • In Pseudomonas aeruginosa, the arginine-inducible succinylornithine transaminase, EC 2.6.1.11 and EC 2.6.1.13 activities are catalyzed by the same enzyme, but this is not the case in all species.
  • This is the third enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine.
  • This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA.
  • The five enzymes involved in this pathway are EC 2.3.1.109, EC 3.5.3.23, EC 2.6.1.81, EC 1.2.1.71 and EC 3.5.1.96.
Cross-references
BRENDA2.6.1.81
EC2PDB2.6.1.81
ExplorEnz2.6.1.81
KEGG Ligand Database for Enzyme Nomenclature2.6.1.81
IUBMB Enzyme Nomenclature2.6.1.81
MEDLINEFind literature relating to 2.6.1.81
MetaCyc2.6.1.81
Rhea expert-curated reactions2.6.1.81
UniProtKB/Swiss-Prot
O30508, ARUC_PSEAEA8AHE0, ASTC_CITK8A7ZML6, ASTC_ECO24
B7USC9, ASTC_ECO27B7MAV9, ASTC_ECO45B7L6M2, ASTC_ECO55
Q8X598, ASTC_ECO57B5YQ35, ASTC_ECO5EB7NT29, ASTC_ECO7I
B7MVM7, ASTC_ECO81B7M1G0, ASTC_ECO8AC4ZZA4, ASTC_ECOBW
B1XGK9, ASTC_ECODHA8A0U0, ASTC_ECOHSA1ABS9, ASTC_ECOK1
Q0TH82, ASTC_ECOL5Q8FGZ9, ASTC_ECOL6B1IPI2, ASTC_ECOLC
P77581, ASTC_ECOLIB7N584, ASTC_ECOLUB6IBG8, ASTC_ECOSE
B1LDY3, ASTC_ECOSMQ1RB45, ASTC_ECOUTB7LQ44, ASTC_ESCF3
Q7N2G7, ASTC_PHOLLB5F846, ASTC_SALA4Q57PX9, ASTC_SALCH
B5FJD8, ASTC_SALDCB5QWJ0, ASTC_SALEPB5RB01, ASTC_SALG2
B4TGE0, ASTC_SALHSB4T3Z4, ASTC_SALNSQ5PHC8, ASTC_SALPA
A9N278, ASTC_SALPBC0Q6X9, ASTC_SALPCB5BA72, ASTC_SALPK
Q8Z6F9, ASTC_SALTIQ8ZPV2, ASTC_SALTYB2U3D0, ASTC_SHIB3
Q321P0, ASTC_SHIBSQ3Z295, ASTC_SHISSA1JS45, ASTC_YERE8
A7FIL6, ASTC_YERP3Q1C8B1, ASTC_YERPAQ8D0D7, ASTC_YERPE
A9QZ63, ASTC_YERPGQ66B21, ASTC_YERPS

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
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