A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 184.108.40.206
View entry in original ENZYME format
View entry in raw text format (no links)
|2-methylpropanoyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine <=> CoA + enzyme N(6)-(S-(2-methylpropanoyl)dihydrolipoyl)lysine|
- A multimer (24-mer) of this enzyme forms the core of the multienzyme
3-methyl-2-oxobutanoate dehydrogenase complex, and binds tightly both
EC 220.127.116.11 and EC 18.104.22.168.
- The lipoyl group of this enzyme is reductively 2-methylpropanoylated
by EC 22.214.171.124, and the only observed direction catalyzed by
EC 126.96.36.199 is that where this 2-methylpropanoyl is passed to
- In addition to the 2-methylpropanoyl group, formed when EC 188.8.131.52
acts on the oxoacid that corresponds with valine, this enzyme also
transfers the 3-methylbutanoyl and S-2-methylbutanoyl groups, donated
to it when EC 184.108.40.206 acts on the oxo acids corresponding with
leucine and isoleucine.
|PRIAM enzyme-specific profiles||220.127.116.11|
|KEGG Ligand Database for Enzyme Nomenclature||18.104.22.168|
|IUBMB Enzyme Nomenclature||22.214.171.124|
|MEDLINE||Find literature relating to 126.96.36.199|
entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-