Accepted Name |
phenolphthiocerol/phthiocerol/phthiodiolone dimycocerosyl transferase
|
Reaction catalysed |
- 2 a mycocerosyl-[mycocerosic acid synthase] + a phthiocerol = a dimycocerosyl phthiocerol + 2 holo-[mycocerosic acid synthase]
- 2 a mycocerosyl-[mycocerosic acid synthase] + a phthiodiolone = a dimycocerosyl phthiodiolone + 2 holo-[mycocerosic acid synthase]
- 2 a mycocerosyl-[mycocerosic acid synthase] + a phenolphthiocerol = a dimycocerosyl phenolphthiocerol + 2 holo-[mycocerosic acid synthase]
|
Comment(s) |
- The enzyme, present in certain pathogenic species of mycobacteria,
catalyzes the transfer of mycocerosic acids to the two hydroxyl
groups at the common lipid core of phthiocerol, phthiodiolone,
and phenolphthiocerol, forming dimycocerosate esters.
- The fatty acid precursors of mycocerosic acids are activated by
EC 6.2.1.49, which loads them onto EC 2.3.1.111.
- That enzyme extends the precursors to form mycocerosic acids that
remain attached until transferred by EC 2.3.1.282.
|
Cross-references |
BRENDA | 2.3.1.282 |
EC2PDB | 2.3.1.282 |
ExplorEnz | 2.3.1.282 |
PRIAM enzyme-specific profiles | 2.3.1.282 |
KEGG Ligand Database for Enzyme Nomenclature | 2.3.1.282 |
IUBMB Enzyme Nomenclature | 2.3.1.282 |
IntEnz | 2.3.1.282 |
MEDLINE | Find literature relating to 2.3.1.282 |
MetaCyc | 2.3.1.282 |
Rhea expert-curated reactions | 2.3.1.282 |
UniProtKB/Swiss-Prot |
Q02279, PAPA5_MYCBO | A1KMT4, PAPA5_MYCBP | Q49939, PAPA5_MYCLE |
A3Q0G0, PAPA5_MYCSJ | A1UGV8, PAPA5_MYCSK | Q1B849, PAPA5_MYCSS |
A5U6U6, PAPA5_MYCTA | P9WIN4, PAPA5_MYCTO | P9WIN5, PAPA5_MYCTU |
A0PQ31, PAPA5_MYCUA | A1T9S1, PAPA5_MYCVP |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
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