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ENZYME entry: EC 3.3.2.8

Accepted Name
Limonene-1,2-epoxide hydrolase.
Alternative Name(s)
Limonene oxide hydrolase.
Reaction catalysed
1,2-epoxymenth-8-ene + H(2)O <=> menth-8-ene-1,2-diol
Comment(s)
  • Involved in the monoterpene degradation pathway of the actinomycete Rhodococcus erythropolis.
  • The enzyme hydrolyzes several alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide.
  • It differs from the previously described epoxide hydrolases (EC 3.3.2.4, EC 3.3.2.6, EC 3.3.2.7, EC 3.3.2.9 and EC 3.3.2.10) as it is not inhibited by 2-bromo-4'-nitroacetophenone, diethyl pyrocarbonate, 4-fluorochalcone oxide or 1,10-phenanthroline.
Cross-references
BRENDA3.3.2.8
EC2PDB3.3.2.8
ExplorEnz3.3.2.8
PRIAM enzyme-specific profiles3.3.2.8
KEGG Ligand Database for Enzyme Nomenclature3.3.2.8
IUBMB Enzyme Nomenclature3.3.2.8
IntEnz3.3.2.8
MEDLINEFind literature relating to 3.3.2.8
MetaCyc3.3.2.8
Rhea expert-curated reactions3.3.2.8
UniProtKB/Swiss-Prot
Q9ZAG3, LIMA_RHOER

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