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ENZYME

ENZYME entry: EC 4.1.3.42

PURL: https://purl.expasy.org/enzyme/EC/4.1.3.42
Accepted Name
(4S)-4-hydroxy-2-oxoglutarate aldolase
Alternative Name(s)
2-keto-4-hydroxyglutaric aldolase
4-hydroxy-2-ketoglutaric aldolase
hydroxyketoglutaric aldolase
Reaction catalysed
(4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate
Comment(s)
  • The enzyme from the bacterium Escherichia coli is specific for the (S) enantiomer.
  • That enzyme is trifunctional, and also catalyzes the reactions of EC 4.1.1.3 and EC 4.1.2.14. cf. EC 4.1.3.16.
Cross-references
BRENDA4.1.3.42
EC2PDB4.1.3.42
ExplorEnz4.1.3.42
KEGG Ligand Database for Enzyme Nomenclature4.1.3.42
IUBMB Enzyme Nomenclature4.1.3.42
MEDLINEFind literature relating to 4.1.3.42
MetaCyc4.1.3.42
Rhea expert-curated reactions4.1.3.42
UniProtKB/Swiss-Prot
P0A957, ALKH_ECO57P0A956, ALKH_ECOL6P0A955, ALKH_ECOLI
P0A958, ALKH_SHIFL

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-