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ENZYME entry: EC 4.1.3.42

Accepted Name
(4S)-4-hydroxy-2-oxoglutarate aldolase.
Alternative Name(s)
2-keto-4-hydroxyglutaric aldolase.
4-hydroxy-2-ketoglutaric aldolase.
Hydroxyketoglutaric aldolase.
Reaction catalysed
(4S)-4-hydroxy-2-oxoglutarate <=> pyruvate + glyoxylate
Comment(s)
  • The enzyme from the bacterium Escherichia coli is specific for the (S) enantiomer.
  • That enzyme is trifunctional, and also catalyzes the reactions of EC 4.1.1.3 and EC 4.1.2.14.
  • Cf. EC 4.1.3.16.
Cross-references
BRENDA4.1.3.42
EC2PDB4.1.3.42
ExplorEnz4.1.3.42
PRIAM enzyme-specific profiles4.1.3.42
KEGG Ligand Database for Enzyme Nomenclature4.1.3.42
IUBMB Enzyme Nomenclature4.1.3.42
IntEnz4.1.3.42
MEDLINEFind literature relating to 4.1.3.42
MetaCyc4.1.3.42
Rhea expert-curated reactions4.1.3.42

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-