- The enzyme cleaves a carbon-carbon bond, releasing indole and an
unstable enamine product that tautomerizes to an imine form, which
undergoes a hydrolytic deamination to form pyruvate and ammonia.
- The latter reaction, which can occur spontaneously, can also be
catalyzed by EC 3.5.99.10.
- Also catalyzes 2,3-elimination and beta-replacement reactions of some
indole-substituted tryptophan analogs of L-cysteine, L-serine and
other 3-substituted amino acids.
|
| UniProtKB/Swiss-Prot |
| P31014, TNAA1_SYMTH; | P31015, TNAA2_SYMTH; | A0KJP3, TNAA_AERHH; |
| Q9YCI2, TNAA_AERPE; | A4SNA7, TNAA_AERS4; | Q8R9K5, TNAA_CALS4; |
| Q7NYV9, TNAA_CHRVO; | A8AKE2, TNAA_CITK8; | Q894M8, TNAA_CLOTE; |
| Q729Z3, TNAA_DESVH; | A1VC86, TNAA_DESVV; | A7ZTR3, TNAA_ECO24; |
| B7UMH5, TNAA_ECO27; | B7MGC9, TNAA_ECO45; | B7L853, TNAA_ECO55; |
| Q8XB34, TNAA_ECO57; | B5YXB2, TNAA_ECO5E; | B7NR10, TNAA_ECO7I; |
| B7N212, TNAA_ECO81; | B7M560, TNAA_ECO8A; | C4ZYY6, TNAA_ECOBW; |
| B1X9T7, TNAA_ECODH; | A8A6H0, TNAA_ECOHS; | Q0TB00, TNAA_ECOL5; |
| Q8FBV2, TNAA_ECOL6; | B1IX30, TNAA_ECOLC; | P0A853, TNAA_ECOLI; |
| B7NF25, TNAA_ECOLU; | B6I3U1, TNAA_ECOSE; | B1LL35, TNAA_ECOSM; |
| B7LK50, TNAA_ESCF3; | Q4QML4, TNAA_HAEI8; | O07674, TNAA_HAEIF; |
| Q0I3R5, TNAA_HAES1; | B0R7Q6, TNAA_HALS3; | Q9HMV2, TNAA_HALSA; |
| B0UTZ3, TNAA_HISS2; | Q0C406, TNAA_HYPNA; | Q59342, TNAA_KLEAE; |
| Q9CL27, TNAA_PASMU; | Q7N8C9, TNAA_PHOLL; | Q9ZNA8, TNAA_PROIN; |
| P28796, TNAA_PROVU; | O30971, TNAA_RHOCA; | Q2S1V4, TNAA_SALRD; |
| A8G097, TNAA_SHESH; | B2TUR7, TNAA_SHIB3; | Q0SYP7, TNAA_SHIF8; |
| P0A854, TNAA_SHIFL; | A5EYI0, TNAA_VIBC3; | Q9KN05, TNAA_VIBCH; |
| C3LUI5, TNAA_VIBCM; | Q87JQ6, TNAA_VIBPA; | Q8D5Q4, TNAA_VIBVU; |
| Q7MCR1, TNAA_VIBVY; | A1JJH3, TNAA_YERE8; |
|