A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 220.127.116.11
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|L-tyrosine isonitrile synthase.
|L-tyrosine + D-ribulose 5-phosphate <=> (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + hydroxyacetone + formaldehyde + phosphate + H(2)O|
- The enzymes from the bacteria Pseudomonas aeruginosa and Xenorhabdus
nematophila are involved in the biosynthesis of paerucumarin and
- According to the proposed mechanism, the enzyme forms an imine
intermediate composed of linked L-tyrosine and D-ribulose
5-phosphate, followed by loss of the phosphate group and formation of
a beta-keto imine and keto-enol tautomerization.
- This is followed by a C-C bond cleavage, the release of acetol, and a
retro aldol type reaction that releases formaldehyde and forms the
- Cf. EC 18.104.22.168.
|PRIAM enzyme-specific profiles||22.214.171.124|
|KEGG Ligand Database for Enzyme Nomenclature||126.96.36.199|
|IUBMB Enzyme Nomenclature||188.8.131.52|
|MEDLINE||Find literature relating to 184.108.40.206|
entries corresponding to 4.1.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-