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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Biotin--[biotin carboxyl-carrier protein] ligase.
Alternative Name(s)
Acetyl-CoA carboxylase biotin holoenzyme synthetase.
Biotin--[acetyl-CoA carboxylase] synthetase.
Biotin--[acetyl-CoA-carboxylase] ligase.
Biotin--protein ligase.
Reaction catalysed
ATP + biotin + [biotin carboxyl-carrier protein]-L-lysine <=> AMP + diphosphate + [biotin carboxyl-carrier protein]-N(6)-biotinyl-L-lysine
  • The enzyme biotinylates a biotin carboxyl-carrier protein that is part of an acetyl-CoA carboxylase complex, enabling its subsequent carboxylation by EC
  • The carboxyl group is eventually transferred to acetyl-CoA by EC
  • In some organisms the carrier protein is part of EC
PRIAM enzyme-specific profiles6.3.4.15
KEGG Ligand Database for Enzyme Nomenclature6.3.4.15
IUBMB Enzyme Nomenclature6.3.4.15
MEDLINEFind literature relating to
P46363, BIRA_HAEIN;  P29906, BIRA_PARDE;  P37416, BIRA_SALTY;  
P50747, BPL1_HUMAN;  Q920N2, BPL1_MOUSE;  O14353, BPL1_SCHPO;  
P48445, BPL1_YEAST;  Q59014, BPL_METJA;  Q9SL92, HCS1_ARATH;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-