ENZYME entry: EC 1.4.3.5

Accepted Name
Pyridoxal 5'-phosphate synthase.
Alternative Name(s)
PMP oxidase.
Pyridoxamine 5'-phosphate oxidase.
Pyridoxamine phosphate oxidase.
Pyridoxamine-phosphate oxidase.
Pyridoxine (pyridoxamine) 5'-phosphate oxidase.
Pyridoxine (pyridoxamine)phosphate oxidase.
Reaction catalysed
  • Pyridoxamine 5'-phosphate + H(2)O + O(2) <=> pyridoxal 5'-phosphate + NH(3) + H(2)O(2)
  • Pyridoxine 5'-phosphate + O(2) <=> pyridoxal 5'-phosphate + H(2)O(2)
Cofactor(s)
FMN.
Comment(s)
In Escherichia coli, the coenzyme pyridoxal 5'-phosphate is synthesized de novo by a pathway that involves EC 1.2.1.72, EC 1.1.1.290, EC 2.6.1.52, EC 1.1.1.262, EC 2.6.99.2 and EC 1.4.3.5.
Cross-references
PROSITEPDOC00815
BRENDA1.4.3.5
EC2PDB1.4.3.5
ExplorEnz1.4.3.5
PRIAM enzyme-specific profiles1.4.3.5
KEGG Ligand Database for Enzyme Nomenclature1.4.3.5
IUBMB Enzyme Nomenclature1.4.3.5
IntEnz1.4.3.5
MEDLINEFind literature relating to 1.4.3.5
MetaCyc1.4.3.5
UniProtKB/Swiss-Prot
Q9UTQ1, PDX3_SCHPO;  P38075, PDX3_YEAST;  Q8Y1C3, PDXH1_RALSO;  
Q31IR4, PDXH1_THICR;  Q8XS03, PDXH2_RALSO;  Q31E41, PDXH2_THICR;  
B0C079, PDXH_ACAM1;  A1TQY3, PDXH_ACIAC;  Q6F718, PDXH_ACIAD;  
B7ICC6, PDXH_ACIB5;  B2I1H7, PDXH_ACIBC;  B0VNC8, PDXH_ACIBS;  
A3M9W4, PDXH_ACIBT;  B0V9C9, PDXH_ACIBY;  A0LR32, PDXH_ACIC1;  
A5FWR6, PDXH_ACICJ;  A1W7K9, PDXH_ACISJ;  A3N3U7, PDXH_ACTP2;  
B3GZF5, PDXH_ACTP7;  B0BU37, PDXH_ACTPJ;  A6VKX9, PDXH_ACTSZ;  
A0KI46, PDXH_AERHH;  A4SKR0, PDXH_AERS4;  Q8UHC2, PDXH_AGRFC;  
B9JAN3, PDXH_AGRRK;  B9JSN3, PDXH_AGRVS;  Q0VSU8, PDXH_ALCBS;  
B6EQ13, PDXH_ALISL;  Q0A757, PDXH_ALKEH;  B4RVA4, PDXH_ALTMD;  
Q2IHV2, PDXH_ANADE;  Q5PBF2, PDXH_ANAMM;  Q2GJ82, PDXH_ANAPZ;  
Q3MFQ5, PDXH_ANAVT;  A8EV17, PDXH_ARCB4;  A8HRJ3, PDXH_AZOC5;  
C1DEH4, PDXH_AZOVD;  Q5LFJ5, PDXH_BACFN;  Q64WC2, PDXH_BACFR;  
Q8A7E7, PDXH_BACTN;  A1URW0, PDXH_BARBK;  Q6G4D7, PDXH_BARHE;  
Q6G0E0, PDXH_BARQU;  Q1LU04, PDXH_BAUCH;  Q6MK45, PDXH_BDEBA;  
Q7VR53, PDXH_BLOFL;  Q492T8, PDXH_BLOPB;  Q2KVR0, PDXH_BORA1;  
Q7WG77, PDXH_BORBR;  Q7W4Q1, PDXH_BORPA;  A9I847, PDXH_BORPD;  
Q7VU72, PDXH_BORPE;  Q89RY8, PDXH_BRADU;  A5EEN4, PDXH_BRASB;  
A4YQ21, PDXH_BRASO;  B2S9Q7, PDXH_BRUA1;  Q2YMD1, PDXH_BRUA2;  
Q57EU9, PDXH_BRUAB;  A9M8J1, PDXH_BRUC2;  C0RHC3, PDXH_BRUMB;  
Q8YFK3, PDXH_BRUME;  A5VNZ1, PDXH_BRUO2;  B0CKA2, PDXH_BRUSI;  
Q8G2A9, PDXH_BRUSU;  B1YVG1, PDXH_BURA4;  Q1BU45, PDXH_BURCA;  
B1JXH8, PDXH_BURCC;  A0K9Z1, PDXH_BURCH;  B4E9I1, PDXH_BURCJ;  
Q0BCF1, PDXH_BURCM;  Q39DH2, PDXH_BURL3;  A9AGI1, PDXH_BURM1;  
A3MHF0, PDXH_BURM7;  A2S933, PDXH_BURM9;  Q62M91, PDXH_BURMA;  
A1V1A2, PDXH_BURMS;  A3NS64, PDXH_BURP0;  Q3JVD0, PDXH_BURP1;  
A3N6I1, PDXH_BURP6;  Q63WN7, PDXH_BURPS;  Q2T0M6, PDXH_BURTA;  
A4JHA1, PDXH_BURVG;  Q13UP6, PDXH_BURXL;  Q20939, PDXH_CAEEL;  
B8H292, PDXH_CAUCN;  Q9A9Q6, PDXH_CAUCR;  Q11KF1, PDXH_CHESB;  
Q1QWA6, PDXH_CHRSD;  Q7P203, PDXH_CHRVO;  A8AH19, PDXH_CITK8;  
Q487G8, PDXH_COLP3;  Q83D18, PDXH_COXBU;  A7MMK2, PDXH_CROS8;  
Q1LK07, PDXH_CUPMC;  Q0K7Z0, PDXH_CUPNH;  Q474I9, PDXH_CUPPJ;  
B3R5Q8, PDXH_CUPTR;  B1WR90, PDXH_CYAA5;  B8HMK7, PDXH_CYAP4;  
B7K9I2, PDXH_CYAP7;  B7JZR4, PDXH_CYAP8;  Q11U72, PDXH_CYTH3;  
C1D0Z0, PDXH_DEIDV;  Q1J188, PDXH_DEIGD;  Q9RX20, PDXH_DEIRA;  
A5EXX0, PDXH_DICNV;  A7ZMA0, PDXH_ECO24;  B7URX9, PDXH_ECO27;  
B7M9Z2, PDXH_ECO45;  B7L5J1, PDXH_ECO55;  Q8X647, PDXH_ECO57;  
B5Z472, PDXH_ECO5E;  B7NTZ4, PDXH_ECO7I;  B7MVB6, PDXH_ECO81;  
B7M0J5, PDXH_ECO8A;  C4ZYA1, PDXH_ECOBW;  B1XFV0, PDXH_ECODH;  
A8A0I1, PDXH_ECOHS;  A1ABI3, PDXH_ECOK1;  Q0THJ0, PDXH_ECOL5;  
Q8FH87, PDXH_ECOL6;  B1IQB6, PDXH_ECOLC;  P0AFI7, PDXH_ECOLI;  
B7NB92, PDXH_ECOLU;  B6IB77, PDXH_ECOSE;  B1LEP8, PDXH_ECOSM;  
Q1RBF7, PDXH_ECOUT;  C5BE32, PDXH_EDWI9;  Q3YSS1, PDXH_EHRCJ;  
Q2GFR2, PDXH_EHRCR;  Q5FH81, PDXH_EHRRG;  Q5HBZ2, PDXH_EHRRW;  
A4W9V9, PDXH_ENT38;  B2VEN4, PDXH_ERWT9;  Q2N6B2, PDXH_ERYLH;  
B7LQN2, PDXH_ESCF3;  A5FB76, PDXH_FLAJ1;  A6H098, PDXH_FLAPJ;  
Q0RUF3, PDXH_FRAAA;  Q2JGW9, PDXH_FRASC;  Q5FPH2, PDXH_GLUOX;  
Q0BVM8, PDXH_GRABC;  A0M2G0, PDXH_GRAFK;  Q7VP83, PDXH_HAEDU;  
Q4QM38, PDXH_HAEI8;  P44909, PDXH_HAEIN;  Q2SDP4, PDXH_HAHCH;  
A1WXY4, PDXH_HALHL;  A4G883, PDXH_HERAR;  Q0C3Z2, PDXH_HYPNA;  
Q5QTW7, PDXH_IDILO;  A6T1X9, PDXH_JANMA;  Q28PH0, PDXH_JANSC;  
A6WE21, PDXH_KINRD;  A6T9Y6, PDXH_KLEP7;  Q5X7K4, PDXH_LEGPA;  
A5IH19, PDXH_LEGPC;  Q5ZY37, PDXH_LEGPH;  Q5WZ02, PDXH_LEGPL;  
B0SGE9, PDXH_LEPBA;  Q04R37, PDXH_LEPBJ;  Q04ZE7, PDXH_LEPBL;  
B0SPV0, PDXH_LEPBP;  B1XYE2, PDXH_LEPCP;  Q72PF1, PDXH_LEPIC;  
Q8F6Y3, PDXH_LEPIN;  Q2W8Y5, PDXH_MAGSA;  Q65QT9, PDXH_MANSM;  
A1TWZ3, PDXH_MARHV;  Q0ARD7, PDXH_MARMM;  A2SJZ5, PDXH_METPP;  
B0JI39, PDXH_MICAN;  A0QBI8, PDXH_MYCA1;  P65683, PDXH_MYCBO;  
A1KLV7, PDXH_MYCBP;  C1AF78, PDXH_MYCBT;  A4T792, PDXH_MYCGI;  
O33065, PDXH_MYCLE;  Q742K7, PDXH_MYCPA;  A0R420, PDXH_MYCS2;  
A3Q628, PDXH_MYCSJ;  A1ULM8, PDXH_MYCSK;  Q1B3H2, PDXH_MYCSS;  
A5U5V8, PDXH_MYCTA;  P9WIJ0, PDXH_MYCTO;  P9WIJ1, PDXH_MYCTU;  
A1TF46, PDXH_MYCVP;  P21159, PDXH_MYXXA;  Q1DCS1, PDXH_MYXXD;  
Q5F8V2, PDXH_NEIG1;  B4RM90, PDXH_NEIG2;  A9M007, PDXH_NEIM0;  
Q9JTZ1, PDXH_NEIMA;  Q9JYZ5, PDXH_NEIMB;  A1KUI2, PDXH_NEIMF;  
Q1QQ51, PDXH_NITHX;  Q3SV02, PDXH_NITWN;  Q5Z236, PDXH_NOCFA;  
A1SEM4, PDXH_NOCSJ;  B2IX27, PDXH_NOSP7;  Q8YXG5, PDXH_NOSS1;  
Q2GCC6, PDXH_NOVAD;  A6WWA8, PDXH_OCHA4;  A1B0C6, PDXH_PARDP;  
A7HR80, PDXH_PARL1;  B2JDT0, PDXH_PARP8;  B2SY78, PDXH_PARPJ;  
Q6D5V3, PDXH_PECAS;  Q4FN05, PDXH_PELUB;  Q7N3W5, PDXH_PHOLL;  
Q6LFS0, PDXH_PHOPR;  A1VRL0, PDXH_POLNA;  Q126S5, PDXH_POLSJ;  
A4SWL7, PDXH_POLSQ;  B2RHS7, PDXH_PORG3;  Q7MU50, PDXH_PORGI;  
A2CDU4, PDXH_PROM3;  B4EWL7, PDXH_PROMH;  Q7V3Y6, PDXH_PROMM;  
Q48LQ7, PDXH_PSE14;  Q15R35, PDXH_PSEA6;  A6V9E9, PDXH_PSEA7;  
B7UXE2, PDXH_PSEA8;  Q02IL5, PDXH_PSEAB;  Q9I4S5, PDXH_PSEAE;  
Q1IDT9, PDXH_PSEE4;  Q4KH71, PDXH_PSEF5;  C3K863, PDXH_PSEFS;  
Q3IDP4, PDXH_PSEHT;  A4XS85, PDXH_PSEMY;  A5VZL6, PDXH_PSEP1;  
Q3KGY4, PDXH_PSEPF;  B0KUA9, PDXH_PSEPG;  Q88NS5, PDXH_PSEPK;  
B1J1C4, PDXH_PSEPW;  Q87XR0, PDXH_PSESM;  Q4ZPN9, PDXH_PSEU2;  
A4VJR0, PDXH_PSEU5;  Q4FS02, PDXH_PSYA2;  Q1QC15, PDXH_PSYCK;  
A1SUY2, PDXH_PSYIN;  A5WEW5, PDXH_PSYWF;  B2U826, PDXH_RALPJ;  
B3PSA1, PDXH_RHIE6;  Q2KBN4, PDXH_RHIEC;  Q1MKJ4, PDXH_RHIL3;  
Q986A0, PDXH_RHILO;  B5ZSU2, PDXH_RHILW;  Q92RH8, PDXH_RHIME;  
C3MHI2, PDXH_RHISN;  Q7UKQ9, PDXH_RHOBA;  Q21WR9, PDXH_RHOFT;  
Q0S6R1, PDXH_RHOJR;  Q2J0U5, PDXH_RHOP2;  Q07HS0, PDXH_RHOP5;  
Q6NAI9, PDXH_RHOPA;  Q21A86, PDXH_RHOPB;  Q13BJ4, PDXH_RHOPS;  
B3QIK5, PDXH_RHOPT;  Q2RR21, PDXH_RHORT;  A3PIG5, PDXH_RHOS1;  
Q3J3Y3, PDXH_RHOS4;  Q163Z1, PDXH_ROSDO;  Q1ATH8, PDXH_RUBXD;  
Q5LRI7, PDXH_RUEPO;  Q1GHI5, PDXH_RUEST;  A1AW86, PDXH_RUTMC;  
Q21IG1, PDXH_SACD2;  A4F7G2, PDXH_SACEN;  B5F6J9, PDXH_SALA4;  
A8M0C0, PDXH_SALAI;  Q57PI9, PDXH_SALCH;  B5FIF5, PDXH_SALDC;  
B5QV11, PDXH_SALEP;  B5RAL1, PDXH_SALG2;  B4THC5, PDXH_SALHS;  
B4T585, PDXH_SALNS;  Q5PIK6, PDXH_SALPA;  A9N035, PDXH_SALPB;  
C0Q5T4, PDXH_SALPC;  B5BKC1, PDXH_SALPK;  Q2S544, PDXH_SALRD;  
B4TV07, PDXH_SALSV;  Q8Z6Q2, PDXH_SALTI;  Q8ZPM9, PDXH_SALTY;  
A8GDX9, PDXH_SERP5;  A1S710, PDXH_SHEAM;  B8EAI0, PDXH_SHEB2;  
A3D3G4, PDXH_SHEB5;  A6WM67, PDXH_SHEB8;  A9KY72, PDXH_SHEB9;  
Q12LW9, PDXH_SHEDO;  Q083L3, PDXH_SHEFN;  B0TQX6, PDXH_SHEHH;  
A3QDE1, PDXH_SHELP;  Q8ED71, PDXH_SHEON;  A8H5G0, PDXH_SHEPA;  
A4Y5Z1, PDXH_SHEPC;  A0KVP0, PDXH_SHESA;  A8FWJ0, PDXH_SHESH;  
Q0HJY0, PDXH_SHESM;  Q0HW76, PDXH_SHESR;  A1RKK6, PDXH_SHESW;  
B1KRD7, PDXH_SHEWM;  B2U2D8, PDXH_SHIB3;  Q320Z5, PDXH_SHIBS;  
Q32FD5, PDXH_SHIDS;  Q0T4D9, PDXH_SHIF8;  P0AFI8, PDXH_SHIFL;  
Q3Z1Z4, PDXH_SHISS;  A6U6T5, PDXH_SINMW;  Q2NT03, PDXH_SODGM;  
Q1GVE7, PDXH_SPHAL;  A5VFM5, PDXH_SPHWW;  Q82GN9, PDXH_STRAW;  
Q9K3V7, PDXH_STRCO;  P74211, PDXH_SYNY3;  C5BN92, PDXH_TERTT;  
Q8DLZ5, PDXH_THEEB;  Q47TD1, PDXH_THEFY;  A1WL02, PDXH_VEREI;  
A5CX08, PDXH_VESOH;  A5F176, PDXH_VIBC3;  A7N7P0, PDXH_VIBCB;  
Q9KKM4, PDXH_VIBCH;  C3LWZ1, PDXH_VIBCM;  Q5DYB5, PDXH_VIBF1;  
B5EVT2, PDXH_VIBFM;  Q87FE9, PDXH_VIBPA;  B7VPY4, PDXH_VIBTL;  
Q8D510, PDXH_VIBVU;  Q7MBT9, PDXH_VIBVY;  Q8D2L7, PDXH_WIGBR;  
Q73G09, PDXH_WOLPM;  Q8PI89, PDXH_XANAC;  Q3BQS3, PDXH_XANC5;  
Q4UX84, PDXH_XANC8;  Q8P6X5, PDXH_XANCP;  Q2P6C7, PDXH_XANOM;  
Q5H3H2, PDXH_XANOR;  A7II77, PDXH_XANP2;  Q9PDP2, PDXH_XYLFA;  
Q87DU7, PDXH_XYLFT;  A1JNV9, PDXH_YERE8;  A7FHL9, PDXH_YERP3;  
Q1C790, PDXH_YERPA;  Q8ZE19, PDXH_YERPE;  A9QZ96, PDXH_YERPG;  
Q1CIM4, PDXH_YERPN;  Q66A48, PDXH_YERPS;  Q9RNP3, PDXH_ZYMMO;  
Q5E9K3, PNPO_BOVIN;  Q54YS6, PNPO_DICDI;  Q9NVS9, PNPO_HUMAN;  
Q91XF0, PNPO_MOUSE;  O88794, PNPO_RAT;  Q9LTX3, PPOX1_ARATH;  
Q9ZPY1, PPOX2_ARATH;  O06553, Y1155_MYCTU;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.4.3.-
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