Due to scheduled maintenance work, this service may not be available on Monday January 22nd between 08.00 am and 9.00 am CEST.
To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC 2.1.1.113

Accepted Name
Site-specific DNA-methyltransferase (cytosine-N(4)-specific).
Alternative Name(s)
Modification methylase.
N(4)-cytosine-specific DNA methylase.
Restriction-modification system.
Reaction catalysed
S-adenosyl-L-methionine + DNA cytosine <=> S-adenosyl-L-homocysteine + DNA N(4)-methylcytosine
Comment(s)
  • This is a large group of enzymes, the majority of which, with enzymes of similar site specificity listed as EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5, form so-called restriction-modification systems.
  • See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
Cross-references
PROSITEPDOC00088
BRENDA2.1.1.113
EC2PDB2.1.1.113
ExplorEnz2.1.1.113
PRIAM enzyme-specific profiles2.1.1.113
KEGG Ligand Database for Enzyme Nomenclature2.1.1.113
IUBMB Enzyme Nomenclature2.1.1.113
IntEnz2.1.1.113
MEDLINEFind literature relating to 2.1.1.113
MetaCyc2.1.1.113
UniProtKB/Swiss-Prot
P0A462, MTA1_ANAVA;  P0A461, MTA1_NOSS1;  P23941, MTB1_BACAM;  
O68556, MTB1_BACIU;  Q9LAI2, MTB1_BACSQ;  P70986, MTB1_GEOSE;  
P18051, MTB2_BACAM;  Q45489, MTB2_BACIU;  Q04845, MTC1_CITFR;  
P14243, MTC9_CITFR;  P29568, MTHZ_METTF;  Q58392, MTM1_METJA;  
Q58843, MTM2_METJA;  Q58893, MTM5_METJA;  Q58606, MTM6_METJA;  
P14244, MTMV_KOCVA;  O59647, MTMW_METWO;  P11409, MTP2_PROHU;  
O52692, MTS1_STRCS;  O52513, MTS1_STRFI;  P14230, MTSM_SERMA;  
P30774, MTX1_XANCC;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-