ENZYME entry: EC 2.1.1.113
| Accepted Name |
|---|
| Site-specific DNA-methyltransferase (cytosine-N(4)-specific).
|
| Alternative Name(s) |
|---|
| Modification methylase. |
| N(4)-cytosine-specific DNA methylase. |
| Restriction-modification system. |
| Reaction catalysed |
|---|
| S-adenosyl-L-methionine + DNA cytosine <=> S-adenosyl-L-homocysteine + DNA N(4)-methylcytosine |
| Comment(s) |
|---|
- This is a large group of enzymes, the majority of which, with enzymes
of similar site specificity listed as EC 3.1.21.3, EC 3.1.21.4 and
EC 3.1.21.5, form so-called restriction-modification systems.
- See the REBASE database for a complete list of these enzymes:
http://rebase.neb.com/rebase/
|
| Cross-references |
|---|
| PROSITE | PDOC00088 |
| BRENDA | 2.1.1.113 |
| EC2PDB | 2.1.1.113 |
| ExplorEnz | 2.1.1.113 |
| PRIAM enzyme-specific profiles | 2.1.1.113 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.113 |
| IUBMB Enzyme Nomenclature | 2.1.1.113 |
| IntEnz | 2.1.1.113 |
| MEDLINE | Find literature relating to 2.1.1.113 |
| MetaCyc | 2.1.1.113 |
| UniProtKB/Swiss-Prot |
| P0A462, MTA1_ANAVA; | P0A461, MTA1_NOSS1; | P23941, MTB1_BACAM; |
| O68556, MTB1_BACIU; | Q9LAI2, MTB1_BACSQ; | P70986, MTB1_GEOSE; |
| P18051, MTB2_BACAM; | Q45489, MTB2_BACIU; | Q04845, MTC1_CITFR; |
| P14243, MTC9_CITFR; | P29568, MTHZ_METTF; | Q58392, MTM1_METJA; |
| Q58843, MTM2_METJA; | Q58893, MTM5_METJA; | Q58606, MTM6_METJA; |
| P14244, MTMV_MICVA; | O59647, MTMW_METWO; | P11409, MTP2_PROHU; |
| O52692, MTS1_STRCS; | O52513, MTS1_STRFI; | P14230, MTSM_SERMA; |
| P30774, MTX1_XANCC; |
|
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