Home  |  Contact

A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.8.98.6

Accepted Name
Formate:CoB-CoM heterodisulfide,ferredoxin reductase.
Reaction catalysed
2 CO(2) + 2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H(+) <=> 2 formate + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB
Comment(s)
  • The enzyme is found in formate-oxidizing CO(2)-reducing methanogenic archaea such as Methanococcus maripaludis.
  • It consists of a cytoplasmic complex of HdrABC reductase and formate dehydrogenase.
  • Electron pairs donated by formate dehydrogenase are transferred to the HdrA subunit of the reductase, where they are bifurcated, reducing both ferredoxin and CoB-CoM heterodisulfide.
  • Cf. EC 1.8.7.3, EC 1.8.98.4, EC 1.8.98.5, and EC 1.8.98.1.
Cross-references
BRENDA1.8.98.6
EC2PDB1.8.98.6
ExplorEnz1.8.98.6
PRIAM enzyme-specific profiles1.8.98.6
KEGG Ligand Database for Enzyme Nomenclature1.8.98.6
IUBMB Enzyme Nomenclature1.8.98.6
IntEnz1.8.98.6
MEDLINEFind literature relating to 1.8.98.6
MetaCyc1.8.98.6
UniProtKB/Swiss-Prot
Q6LWL2, HDRA_METMP;  Q6LY38, HDRB1_METMP;  Q6LYD8, HDRB2_METMP;  
Q6LY39, HDRC1_METMP;  Q6LYD7, HDRC2_METMP;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.98.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-