Expasy logo

ENZYME

ENZYME entry: EC 5.4.99.18

PURL: https://purl.expasy.org/enzyme/EC/5.4.99.18
Accepted Name
5-(carboxyamino)imidazole ribonucleotide mutase
Alternative Name(s)
N(5)-CAIR mutase
N(5)-carboxyaminoimidazole ribonucleotide mutase
Reaction catalysed
5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate
Comment(s)
  • In eubacteria, fungi and plants, this enzyme, along with EC 6.3.4.18, is required to carry out the single reaction catalyzed by EC 4.1.1.21 in vertebrates.
  • In the absence of EC 6.3.2.6, the reaction is reversible.
  • The substrate is readily converted into 5-amino-1-(5-phospho-D- ribosyl)imidazole by non-enzymic decarboxylation.
Cross-references
BRENDA5.4.99.18
EC2PDB5.4.99.18
ExplorEnz5.4.99.18
KEGG Ligand Database for Enzyme Nomenclature5.4.99.18
IUBMB Enzyme Nomenclature5.4.99.18
MEDLINEFind literature relating to 5.4.99.18
MetaCyc5.4.99.18
Rhea expert-curated reactions5.4.99.18
UniProtKB/Swiss-Prot
Q5E1R4, PURE_ALIF1O67239, PURE_AQUAEP12044, PURE_BACSU
P52558, PURE_BRUMEQ8FYW3, PURE_BRUSUQ44679, PURE_CORAM
P0AG19, PURE_ECO57P0AG18, PURE_ECOLIP43849, PURE_HAEIN
Q58033, PURE_METJAP22348, PURE_METSMP41654, PURE_METTH
P46702, PURE_MYCLEP9WHM0, PURE_MYCTOP9WHM1, PURE_MYCTU
P72157, PURE_PSEAEQ9UY68, PURE_PYRABO58058, PURE_PYRHO
O06456, PURE_SACS2Q55498, PURE_SYNY3Q9WYS7, PURE_THEMA
Q9KVT7, PURE_VIBCHQ87KE1, PURE_VIBPAQ8DDD7, PURE_VIBVU
Q7MGL2, PURE_VIBVY

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.4.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-