ENZYME entry: EC 5.4.99.18
Accepted Name |
5-(carboxyamino)imidazole ribonucleotide mutase.
|
Alternative Name(s) |
N(5)-CAIR mutase. |
N(5)-carboxyaminoimidazole ribonucleotide mutase. |
Reaction catalysed |
5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole <=> 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate |
Comment(s) |
- In eubacteria, fungi and plants, this enzyme, along with EC 6.3.4.18,
is required to carry out the single reaction catalyzed by EC 4.1.1.21
in vertebrates.
- In the absence of EC 6.3.2.6, the reaction is reversible.
- The substrate is readily converted into 5-amino-1-(5-phospho-D-
ribosyl)imidazole by non-enzymic decarboxylation.
|
Cross-references |
BRENDA | 5.4.99.18 |
EC2PDB | 5.4.99.18 |
ExplorEnz | 5.4.99.18 |
PRIAM enzyme-specific profiles | 5.4.99.18 |
KEGG Ligand Database for Enzyme Nomenclature | 5.4.99.18 |
IUBMB Enzyme Nomenclature | 5.4.99.18 |
IntEnz | 5.4.99.18 |
MEDLINE | Find literature relating to 5.4.99.18 |
MetaCyc | 5.4.99.18 |
UniProtKB/Swiss-Prot |
Q5E1R4, PURE_ALIF1; | O67239, PURE_AQUAE; | P12044, PURE_BACSU; |
P52558, PURE_BRUME; | Q8FYW3, PURE_BRUSU; | Q44679, PURE_CORAM; |
P0AG19, PURE_ECO57; | P0AG18, PURE_ECOLI; | P43849, PURE_HAEIN; |
Q58033, PURE_METJA; | P22348, PURE_METSM; | P41654, PURE_METTH; |
P46702, PURE_MYCLE; | P9WHM0, PURE_MYCTO; | P9WHM1, PURE_MYCTU; |
P72157, PURE_PSEAE; | Q9UY68, PURE_PYRAB; | O58058, PURE_PYRHO; |
O06456, PURE_SACS2; | Q55498, PURE_SYNY3; | Q9WYS7, PURE_THEMA; |
Q9KVT7, PURE_VIBCH; | Q87KE1, PURE_VIBPA; | Q8DDD7, PURE_VIBVU; |
Q7MGL2, PURE_VIBVY; |
|
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